Sökning: "N-terminal region"

Visar resultat 6 - 10 av 137 avhandlingar innehållade orden N-terminal region.

1. 6. Molecular studies on streptococcal surface proteins

   Författare :Johan Waldemarsson; Avdelningen för medicinsk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nonimmunodominance; vaccine; camouflaging; Streptococcus agalactiae; leucine-rich repeat; Streptococcus pyogenes; alpha; fibrinogen; M protein; surface proteins; Rib;

   Sammanfattning : Streptococcus agalactiae and Streptococcus pyogenes are two related human pathogens causing different diseases. This thesis focuses on a number of surface proteins expressed by S. agalactiae and S. pyogenes and, more specifically, the molecular and biological characterization of these proteins. LÄS MER

3. 7. Dual targeting of proteins to mitochondria and chloroplasts : Characterization of dual targeting peptides and their interaction with organellar receptors

   Författare :Erika Spånning; Elzbieta Glaser; Anthony Moore; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

   Sammanfattning : Most mitochondrial and chloroplastic proteins are synthesized in the cytosol as precursor proteins with an N-terminal targeting peptide (TP), which directs them to the correct organelle. There is also a group of proteins that are dual targeted to mitochondria and chloroplasts using an ambiguous N-terminal dual targeting peptide (dTP). LÄS MER

4. 8. The molecular features in PKC epsilon determining its neurite-inducing capacity

   Författare :Mia Ling; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; neuroblastoma; neurite outgrowth; C1 domain; cancerology; cancer; onkologi; Cytologi; protein kinase C;

   Sammanfattning : Protein kinase C (PKC) is a family of serine/threonine kinases which are subgrouped into classical (a, bI, bII, g), novel (d, e, h, q) and atypical (z, i/l) isoforms. It has been shown that PKCe induces neurite outgrowth in neuroblastoma cells and the effect is mediated via the regulatory domain. LÄS MER

5. 9. Structural and biophysical studies of pneumococcal capsular surface proteins

   Författare :Cecilia Mikaelsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Streptococcus pneumoniae (pneumococcus) is a major human pathogen and a leading cause of morbidity and mortality worldwide, especially in children and the elderly. The casualties due to respiratory infections are estimated to be over 4 million per year, where pneumococcus is the predominant species. LÄS MER

7. 10. Regulatory mechanisms of amino acid-induced signaling in Saccharomyces cerevisiae

   Författare :Deike J. Omnus; Per O. Ljungdahl; Claudio De Virgilio; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Signal transduction; regulatory mechanisms; nutrient sensing; Saccharomyces cerevisiae; Cell Biology; cellbiologi;

   Sammanfattning : This thesis describes studies aimed at elucidating the molecular mechanisms that regulate the SPS (Ssy1-Ptr3-Ssy5) signal transduction pathway in the yeast Saccharomyces cerevisiae. This pathway is induced by extracellular amino acids and facilitates their uptake. LÄS MER