Sökning: "N-terminal region"

Visar resultat 1 - 5 av 134 avhandlingar innehållade orden N-terminal region.

  1. 1. Coordinating type III secretion system biogenesis in Yersinia pseudotuberculosis

    Författare :Jyoti Mohan Gurung; Matthew S Francis; Maria Fällman; Dirk Linke; Umeå universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; Yersinia pseudotuberculosis; type III secretion system; YscX; YscY; YopN; TyeA; secretion signal; N-terminal region; site-directed mutagenesis; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Sammanfattning : Various Gram-negative bacteria utilize type III secretion system (T3SS) to deliver effectors into eukaryotic host cells and establish mutualistic or pathogenic interactions. An example is the Ysc-Yop T3SS of pathogenic Yersinia species. LÄS MER

  3. 2. The N-terminal EGF Module of Coagulation factor IX. Studies of Calcium Binding and Module Interactions

    Författare :Kristina Persson; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coagulation FIX EGF module calcium binding interaction; Clinical chemistry; Klinisk kemi;

    Sammanfattning : Coagulation factor IX (FIX) is a vitamin K-dependent serine protease zymogen that circulates in plasma. Defects in FIX cause the bleeding disorder hemophilia B. FIX contains a Gla module, two Epidermal Growth Factor (EGF) -like modules and a serine protease region. LÄS MER

  4. 3. Immunological and functional properties of a non-repeat region in Plasmodium falciparum antigen Pf155/RESA

    Författare :Siddique Abu Bakar; Lars Hvid; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

    Sammanfattning : Plasmodium falciparum malaria is one of the most prevalent of all the great insect-borne diseases causing high morbidity and mortality in humans. As conventional anti-malarial treatment is becoming increasingly inefficient, alternative approaches to combat the parasite, like vaccine development, are of high priority. LÄS MER

  5. 4. Human papillomavirus tropism : determinants of viral tissue specificity

    Författare :Nitesh Mistry; Magnus Evander; Ola Forslund; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; papillomavirus; receptor; heparan sulfate; pI; lactoferrin; lactoferricin; transcription; long control region; tropism; Virology; Virologi;

    Sammanfattning : Cervical cancer is the second most common cancer among women worldwide and human papillomavirus (HPV) is a prerequisit for the development of this cancer. HPV belongs to the Papillomaviridae family and infects the basal layer of epithelial cells where it generally progresses into warts or condylomas. LÄS MER

  7. 5. NA transmembrane domain : Amphiphilic drift to accommodate two functions

    Författare :Johan Nordholm; Robert Daniels; Ervin Fodor; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; influenza; IAV; neuraminidase; NA; transmembrane domain; TMD; secretory protein; ER-targeting sequence; ER-targeting sequence coding region; protein regulation; NS1; GALLEX; Biochemistry; biokemi;

    Sammanfattning : Neuraminidase (NA) is one of two major antigens on the surface of influenza A viruses. It is comprised of a single N-terminal transmembrane domain (TMD), a stalk domain, and a C-terminal enzymatic head domain that cleaves sialic acid, most notably to release new particles from the host cell surface. LÄS MER