Sökning: "N-acetylneuraminic acid"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden N-acetylneuraminic acid.

  1. 1. Tailored conjugates of N-acetylneuraminic acid and small molecules that block virus cell attachment and entry

    Författare :Emil Johansson; Mikael Elofsson; Niklas Arnberg; Geert-Jan Boons; Umeå universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; N-acetylneuraminic acid; Neu5Ac; sialic acid; multivalency; Coxsackievirus A24v CVA24v ; Human adenovirus D37; D36; D26; HAdV-D37; HAdV-D26; HAdV-D36 ; 4-O-alkyl Neu5Ac; cryo-EM; branched pleconaril probes; conjunctivitis; organisk kemi; Organic Chemistry;

    Sammanfattning : Viruses are obligate intracellular parasites, unable to replicate without exploiting machinery andmaterials from host cells. Pandemics of viral diseases have had large impacts on human socieities and are continued threats to global health. LÄS MER

  2. 2. Some New Methods in Sialic Acid Chemistry

    Författare :Teddy Ercegovic; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; thioglycoside promoter; ganglioside; Tumor-associated antigen; lactam; lactone; sialic acid; N-acetylneuraminic acid; Neu5Ac; sialyl donor; auxiliary group; 3- S -phenylthio; bis-sialic acid lactam; 3- S -phenylseleno; silver trifluoromethanesulfonate; iodine monochloride; Organic chemistry; Organisk kemi;

    Sammanfattning : Gangliosides (G) are sialic acid-containing cell surface glycosphingolipids capable of forming lactones, i.e. inner esters. Some gangliosides are tumor-associated antigens, and they may serve as immunogens in their lactone form, where the latter is comparatively more abundant on the surface of malignant cells. LÄS MER

  3. 3. Synthesis of N-acetylneuraminic acid derivatives and studies of their interaction with Vibro cholerae neuraminidase

    Författare :Leif Holmquist; Stockholms universitet; []

    Sammanfattning : .... LÄS MER

  4. 4. The glycobiology of human adenovirus infections : implications for tropism and treatment

    Författare :Naresh Chandra; Niklas Arnberg; Lars Frängsmyr; Gunnel Haldén; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; denovirus; cellular receptor; glycosaminoglycan; sialic acid; decoy receptors; tropism; epidemic keratoconjunctivitis; antiviral drugs; GAG-mimetic; obesity; medicinsk virologi; Medical Virology;

    Sammanfattning : Human adenoviruses (HAdVs) are common human pathogens, causing gastrointestinal, ocular, and respiratory infections on a regular basis. Epidemic keratoconjunctivitis (EKC) is a severe ocular infection for which no approved antivirals are available. LÄS MER

  5. 5. Glycan-based interactions of Streptococcus pneumoniae and the host

    Författare :Karina Hentrich; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Streptococcus pneumoniae is commonly found as an asymptomatic colonizer of the nasopharynx of children, but it can also translocate to normally sterile body sites and cause severe diseases, like pneumonia, septicemia or meningitis. Pneumococci spread via aerosols. LÄS MER