Sökning: "N-acetyl transferase"

Hittade 3 avhandlingar innehållade orden N-acetyl transferase.

1. 1. Microsomal glutathione transferase : catalysis, in vitro mutagenesis and heterologous expression

   Författare :Rolf Weinander; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Microsomal glutathione transferase is a membrane-bound member of the glutathione transferases, a family of multifunctional enzymes involved in the cellular detoxification of xenobiotics and reactive endogenous compounds formed during oxidative stress. Rat liver microsomal glutathione transferase is a trimeric protein with a molecular mass of 17. LÄS MER

3. 2. Microsomal glutathione transferase : studies on the kinetic mechanism, species variety, binding properties and substrate measurement

   Författare :Tie-Hua Sun; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Microsomal glutathione transferase (MGST) is a membrane bound detoxification enzyme, which has been purified from different species including rat, mouse, human, frog, and fish. The rat MGST1 is localized predominantly in the liver microsomes and the outer mitochondrial membrane. LÄS MER

4. 3. Environmental and genetic factors in lung cancer : epidemiologocal and biomolecular studies focusing on nonsmokers

   Författare :Fredrik Nyberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Lung cancer; case-control study; smoking misclassification; exposure misclassification; validation; bias; nonsmoker; smoking; environmental tobacco smoke; ETS; diet; biomarker; glutathione S transferase; GSTM1; N-acetyl transferase; NAT2; hypoxanthine-guanine phosphoribosiyl transferase; hprt; DNA; adducts;

   Sammanfattning : Tobacco smoking is the major cause of lung cancer. Other risk factors include exposure to environmental tobacco smoke (ETS), dietary habits and genetic factors. When studying such risk factors, confounding from smoking presents a pervasive methodological problem. LÄS MER