Sökning: "Myogenic tone"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Myogenic tone.

  1. 1. Regulation of the myogenic response and stretch-induced calcium signaling in the vascular wall: Novel insights into the role of microRNAs and protein tyrosine kinase 2

    Författare :Anirban Bhattachariya; Kärlfysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; portal vein; resistance artery; myogenic tone; PYK2; calcium; microRNA;

    Sammanfattning : Intraluminal pressure has a significant impact on vascular adaptability, phenotype and regulation of blood flow and pressure. On one hand, increased pressure/stretch for a prolonged time can cause structural changes in vessel wall; on the other hand, lack of pressure/stretch can promote a phenotype shift. LÄS MER

  3. 2. Regulation of vascular tone in myometrial resistance arteries in normal pregnancy and preeclampsia

    Författare :Karolina Kublickiene; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atrial natriuretic peptide; Blood vessels; Endothelin-l; Endothelin receptors; Myogenic tone; Myometrial Arteries; Preeclampsia; Pregnancy; Nitric oxide; Shear stress; Vascular endothelium; Vascular smooth muscle .;

    Sammanfattning : Background: Normal pregnancy is characterized by the occurrence of substantial vasodilatation. Pressure responsiveness and vascular reactivity to administered vasoconstrictors undergo considerable attenuation. These circulatory changes are essential to maintain adequate oxygen and nutrient delivery to the placenta and thus to the fetus. LÄS MER

  4. 3. Gender-related small artery function : implications for estrogenic compounds

    Författare :Maria-Natalia Cruz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Vascular effects of estrogens have been shown to be mediated by estrogen receptor (ER)α. The discovery of ERβ, which shares many similarities with ERα, brought about a reevaluation of the role of the ER subtypes (ERs) in the vasculature. LÄS MER

  5. 4. Neuromuscular function in the normal and inflamed colon. An experimental study in rat

    Författare :Lars Börjesson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; dextran sulphate sodium; DMPP; enteric nervous system; McN-A-343; nitric oxide; non-adrenergic; rat; second messenger; smooth muscle; VIP;

    Sammanfattning : Neuromuscular function of the longitudinal muscle layer of distal colon was investigated in segments from normal rats and from rats with colitis induced by dextran sulphate sodium (DSS) at 3% for 3 or 7 days or 5% for 7 days. The study was performed in vitro, on spontaneous tone, or after precontraction. LÄS MER

  7. 5. Small artery dysfunction : focus on preeclampsia and end-stage renal disease

    Författare :Natallia Luksha; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :resistance arteries;

    Sammanfattning : Background: End-stage renal disease (ESRD) and preeclampsia (PE) are associated with high risk of cardiovascular events and characterized by endothelial dysfunction. Resistance arteries are actively involved in the control of blood pressure and blood flow to the target organs. LÄS MER