Sökning: "Myogenesis"

Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet Myogenesis.

  1. 1. Molecular mechanisms mediating development of pulmonary cachexia in COPD

    Författare :Vladimir Basic; Jorge Ruas; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; COPD; cachexia; atrophy; cigarette smoke; myogenesis; angiogenesis; Biomedicin; Biomedicine; Biokemi; Biochemistry;

    Sammanfattning : Cigarette smoking (CS) represents the main causative agent underlying development and progress of COPD. Recently, involvement of CS in the pathogenesis of COPDassociated muscle abnormalities is becoming increasingly evident. Nevertheless, involved triggers and underlying mechanisms remain largely unknown. LÄS MER

  3. 2. The role of Six1 in muscle progenitor cells and the establishment of fast-twitch muscle fibres

    Författare :Hanna Nord; Jonas von Hofsten; Freek van Eeden; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Myogenesis; zebrafish; muscle fibre; patterning; fmyhc; myl1; Six1; Pax7;

    Sammanfattning : Myogenesis is the process of skeletal muscle tissue formation where committed muscle progenitor cells differentiate into skeletal muscle fibres. Depending on the instructive cues the muscle progenitor cells receive they will differentiate into specific fibre types with different properties. LÄS MER

  4. 3. Cellular studies of neuromuscular disorders related to the sarcomeric proteins

    Författare :Saba Abdul-Hussein; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; myogenesis; myoblast; sarcomeric myopathy; TPM2; TRIM54; TRIM63;

    Sammanfattning : Sarcomere is the basic unit of cardiac and skeletal muscle contraction and its proper function requires an invariant organization of this structure. Mutations in sarcomeric proteins are known to cause increasing number of different cardiac and skeletal muscle diseases. LÄS MER

  5. 4. Nestin : filament formation and expression in myogenesis and muscle disorders

    Författare :Gunnar Sjöberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Intermediate filament; nestin; desmin; vimentin; myogenesis neuromusculardisorders; rhabdomyosarcoma;

    Sammanfattning : Intermediate filaments (IF), together with microfilaments and microtubules, are the major components of the cytoskeleton of eukaryotic cells. In myogenic cells three IF proteins are expressed; desmin, vimentin and nestin. LÄS MER

  7. 5. Calcium regulation and functions of basic Helix-Loop-Helix transcription factors

    Författare :Juha Saarikettu; Thomas Grundström; Dan Holmberg; Mikael Sigvardsson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; calcium; calmodulin; calretinin; transcription; bHLH; E-protein; E2-2; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The members of the ubiquitously expressed E-protein subfamily of basic Helix-Loop-Helix (bHLH) transcription factors, E12/E47, SEF2-1 and HEB, have important roles as regulators of gene expression in various differentiation processes, including lymphocyte development and myogenesis. In myogenesis, E-proteins are proposed to function as obligate heterodimer partners for members of the MyoD family of muscle-specific bHLH transcription factors. LÄS MER