Sökning: "Myocytes"

Visar resultat 1 - 5 av 20 avhandlingar innehållade ordet Myocytes.

  1. 1. Studies on Cell Injury Induced by Hypoxia-Reoxygenation and Oxidized Low Density Lipoprotein : With Special Reference to the Protectiove Effect of Mixed Tocopherols, Omega-3 Fatty Acids and Transforming Growth Factor-beta1

    Författare :Hongjiang Chen; Tom Saldeen; Christer Sylven; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Tocopherols; fish oil; TGF-β1; NOS; adhesion molecules; MMPs; PKB; MAPK; H-R; Ox-LDL; Myocytes; HCAECs; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Hypoxia-reoxygenation (H-R) injury is an important clinical phenomenon in patients with coronary artery disease (CAD). Endothelial injury is a critical step in the initiation and progression of atherosclerosis. Therefore, endothelial and cardiomyocyte protection has been considered an effective step in prevention and treatment of CAD. LÄS MER

  3. 2. Studies on isolated cardiac myocytes with emphasis on their interactions with extracellular matrix components

    Författare :Evy Lundgren; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 3. Mechanism of Action of the Antiarrhythmic Agent AZD7009

    Författare :Frida Persson; Göteborgs universitet; []
    Nyckelord :atrial fibrillation; antiarrhythmic drug; IKr; IKur; Ito; IKs; IKACh; INa; ICaL; cardiac action potential; early afterdepolarisation;

    Sammanfattning : Atrial fibrillation (AF) is the most common tachyarrhythmia in the adult population and is a major cause of morbidity and mortality. AF can be terminated and sinus rhythm restored by prolonging the action potential duration (APD) and the refractory period. LÄS MER

  5. 4. Immunocytochemical visualization of cathepsin D during oxidative stress

    Författare :Karin Roberg; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Cathepsin D is the major aspartic protease in lysosomes, and it is found in almost all animal cells. In the present studies, a pre-embedding immunocytochemical method was used to visualize cathepsin D in cultured cells. The protein can be detected at both light and electron microscopic levels by neutral-pH silver enhancement of ultrasmall (0. LÄS MER

  7. 5. Systems Biology of Type 2 Diabetes in Skeletal Muscle

    Författare :Leif Väremo; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; genome-scale metabolic model; metabolism; skeletal muscle; myocyte; type 2 diabetes; network analysis; gene-set analysis; transcriptomics; gene expression; obesity;

    Sammanfattning : Type 2 diabetes (T2D) is a heterogeneous and complex disease that currently affects more than 350 million people worldwide. A wide range of risk factors influence the pathogenesis of T2D, including genetic and epigenetic components, as well as controllable factors such as diet, obesity, and sedentary lifestyle. LÄS MER