Sökning: "Myelin P2 protein"

Hittade 4 avhandlingar innehållade orden Myelin P2 protein.

  1. 1. Strategies to explore the membrane proteome of a cell

    Författare :Gianluca Maddalo; Leopold L. Ilag; Peter James; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Membrane proteins; Proteomics; Escherichia coli; Enterococcus faecalis; Synechocystis; Mass Spectrometry; BN SDS-PAGE; FT-ICR-MS; Myelin P2 protein; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : The cell envelope plays key roles in numerous processes such as maintaining cellular integrity, communication with other cells, signal transduction, maintenance of cellular homeostasis, and regulation of the traffic of molecules between the cell and the extracellular milieu. Essential membrane components in many of these processes are proteins. LÄS MER

  3. 2. Immunoregulation and immunotherapy in experimental autoimmune neuritis

    Författare :Li-Ping Zou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Experimental autoimmune neuritis (EAN) is a CD4+ T cell mediated autoimmune disease of the peripheral nervous system (PNS). EAN represents an animal model for studying the immunopathogenesis and immunotherapy of Guillain-Barré syndrome (GBS). LÄS MER

  4. 3. Modulation of experimental T cell autoimmunity in the nervous system with emphasis on nasal tolerance

    Författare :Xue-Feng Bai; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Experimental autoimmune neuritis (EAN) and encephalomyelitis (EAE) are animal models of Guillian-Barre syndrome (GBS) and multiple sclerosis (MS), representing human demyelinating diseases of the peripheral nervous system (PNS) and central nervous system (CNS), respectively. CD4+ T cells recognizing myelin antigens and producing cytokines play central roles in the pathogenesis of both EAN and EAE and perhaps of GBS and MS. LÄS MER

  5. 4. Immunomodulation of cytokine and chemokine production in animal models of neuroinflammatory and neurodegenerative disorders

    Författare :Nagat Abbas Ahmed M Gadeh EL Dum; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Experimental autoimmune neuritis (EAN) is a CD4+ T cell-mediated autoimmune disease of the peripheral nervous system (PNS) that can be actively induced in susceptible animal species and strains by active immunization with heterogeneous peripheral nerve myelin or its component P2 or PO proteins or their peptides emulsified in Freund's complete adjuvant. EAN represents an animal model for studying the immunopathogenesis and therapy of Guillain-Barré syndrome (GBS ) which is a major inflammatory demyelinating disease of the PNS in humans. LÄS MER