Sökning: "Mutation"
Visar resultat 21 - 25 av 1258 avhandlingar innehållade ordet Mutation.
21. A Multitype Branching Processes Approach to the Evolutionary Dynamics of Escape
Sammanfattning : Evolutionary dynamics of escape is a recent development in theoretical biology. It is an attempt to predict possible patterns of population dynamics for a certain strain of viruses placed in a hostile environment. The only way to escape extinction for the virus is to find a new form better adapted to the new environment. LÄS MER
22. Gastrointestinal stromal tumors. Pathogenetic mechanisms, phenotypic characterization and prognosis
Sammanfattning : Gastrointestinal stromal tumor (GIST), the most common non-epithelial neoplasm of the gastrointestinal tract, has historically been problematic both conceptually and clinically. Recently, GIST has been shown to share phenotypic features with the interstitial cells of Cajal (ICC), including the almost uniform expression of the tyrosine kinase receptor KIT. LÄS MER
23. Short and long-term effects of exposure to low dose and low dose rate of gamma radiation : using in vitro and in vivo models
Sammanfattning : Assessment of human health risks from exposure to ionizing radiation (IR) is mainly based on the extrapolation of results from epidemiological studies on populations exposed to relatively high doses and often at high dose rates (HDR). Risk estimates after exposure to low doses and in particular at low dose rates (LDR) remain controversial due to a lack of epidemiological evidence. LÄS MER
24. Detection and analysis of genetic alterations in normal skin and skin tumours
Sammanfattning : The investigation of genetic alterations in cancer-relatedgenes is useful for research, prognostic and therapeuticpurposes. However, the genetic heterogeneity that often occursduring tumour progression can make correct analysischallenging. LÄS MER
25. Quantitative analysis of disease associated mutations and sequence variants
Sammanfattning : A solid-phase sequencing technique was applied to quantify the mitochondrial A3243G mutation in three families with maternally inherited diabetes and deafness. A correlation between the level of heteroplasmy and age at onset was found. LÄS MER