Sökning: "Munc-18 Stxbp1"

Hittade 1 avhandling innehållade orden Munc-18 Stxbp1.

1. 1. Exocytosis in Type 2 Diabetes- Functional and genetic studies of hormone secretion

   Författare :Sofia A Andersson; Diabetes - öcellsexocytos; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Insulin; Glucagon; Alpha-cells; Beta-cells; Exocytosis; Capacitance; SNARE; SNAP25; Syntaxin1A; Synaptotagmin; Munc-18 Stxbp1 ; SNP; Expression; miRNA;

   Sammanfattning : Type 2 Diabetes (T2D) is characterized by dysregulated beta-and alpha-cell hormone secretion leading to elevated blood glucose levels. Several proteins are crucial in maintaining exocytosis of the hormone-containing granules such as Syntaxin1A (Stx1A), SNAP25, Munc-18 (Stxbp1) and the family of Synaptotagmins (Syts). LÄS MER