Sökning: "Multiplex"

Visar resultat 1 - 5 av 218 avhandlingar innehållade ordet Multiplex.

1. 1. Selector Technology : For Multiplex DNA Analysis

   Författare :Fredrik Dahl; Mats Nilsson; Ulf Landegren; Ivo Glynne Gut; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Genetic engineering; DNA technology; Genteknik; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

   Sammanfattning : A majority of methods for identifying sequences in the human genome involve target sequence amplification through PCR. This work presents novel methods for amplifying circularized DNA and presents solutions for some major limitations of PCR. LÄS MER

3. 2. Building study-related relationships : How student relationships and readiness affect academic outcome in higher education

   Författare :Annika Maria Fjelkner Pihl; Centre for Engineering Education CEE; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Academic outcome; commuter; readiness; higher education; social network analysis; multiplex relations; Academic outcome; Multiplex relations; Commuters; Higher education; Social network analysis; Readiness;

   Sammanfattning : The present dissertation explores students’ perception of their own readiness for higher education and students’ study related relations and the effect on academic outcome. The complexity of student engagement and academic success means that it is relevant to conduct in-depth studies of particular student populations, to explore how certain factors play out in that specific context. LÄS MER

4. 3. Antibody based plasma protein profiling

   Författare :Ulrika Qundos; Jochen M. Schwenk; Peter Nilsson; Mathias Uhlén; Ulrike Korf; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein profiling; plasma; antibody; affinity proteomics; biomark- ers; multiplex; assay development;

   Sammanfattning : This thesis is about protein profiling in serum and plasma using antibody suspension bead arrays for the analysis of biobanked samples and in the context of prostate cancer biomarker discovery. The influence of sample preparation methods on antibody based protein profiles were investigated (Papers I-III) and a prostate cancer candidate biomarker identified and verified (Papers III-V). LÄS MER

5. 4. Proximity Ligation and Barcoding Assays : Tools for analysis of proteins and protein complexes

   Författare :Di Wu; Masood Kamali-Moghaddam; Ulf Landegren; Ola Söderberg; Jörg Hoheisel; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proximity ligation assay; proximity barcoding assay; sensitive; in situ; multiplex; profiling; amyloid-beta; MARK; tau; CSF; biomarker; protein complexes; Alzheimer’s disease; amyotrophic lateral sclerosis; Molekylär medicin; Molecular Medicine;

   Sammanfattning : Proteins are fundamental structural, enzymatic and regulatory components of cells. Analysis of proteins, such as by measuring their concentrations, characterizing their modifications, and detecting their interactions, provides insights in how biological systems work physiologically or pathologically at the molecular level. LÄS MER

7. 5. Biomarkers in mid-trimester amniotic fluid in relation to gestational duration and spontaneous preterm delivery

   Författare :Maria Hallingström; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amniotic fluid; biomarkers; cytokine; damage-associated molecular pattern; gestation; gestational duration; inflammation; labor; mid-trimester; multiplex; pregnancy clock; proteins; spontaneous preterm delivery; term delivery;

   Sammanfattning : Background: The biological mechanisms and physiological pathways of pregnancy maintenance and timing of delivery are complex and multifactorial. Pregnancy clocks, partly controlled by timing mechanisms linked to fetal development, which regulate the onset of labor has previously been described. LÄS MER