Sökning: "Multiple sclerosis"
Visar resultat 21 - 25 av 309 avhandlingar innehållade orden Multiple sclerosis.
21. Longitudinal Models for Quantifying Disease and Therapeutic Response in Multiple Sclerosis
Sammanfattning : Treatment of patients with multiple sclerosis (MS) and development of new therapies have been challenging due to the disease complexity and slow progression, and the limited sensitivity of available clinical outcomes. Modeling and simulation has become an increasingly important component in drug development and in post-marketing optimization of use of medication. LÄS MER
22. Chronic sorrow and quality of life in patients with multiple sclerosis
Sammanfattning : The overall aim of this thesis was to increase our understanding and knowledge of patients’ experiences of living with multiple sclerosis (MS). A mixed-method design was used, including both qualitative and quantitative methods. LÄS MER
23. Hematopoietic Stem Cell Transplantation for Treatment of Multiple Sclerosis in Sweden
Sammanfattning : This thesis investigated the efficacy and safety of autologous hematopoietic stem cell transplantation (AHSCT) as a treatment of multiple sclerosis. This thesis demonstrates that when compared to one of the most powerful disease-modifying drugs (DMDs), specifically alemtuzumab (ALZ), AHSCT is able to hold its ground. LÄS MER
24. Walking ability, balance and accidental falls in persons with Multiple Sclerosis
Sammanfattning : By using a pragmatic paradigm, different research methodologies were employed in this thesis. MS-related symptoms may be exaggerated due to heatsensitivity and it is supposed that cooling garments relieve the symptoms. LÄS MER
25. Multiple Sclerosis: Studies of the Interferon system and search for infectious agents
Sammanfattning : Multiple sclerosis (MS) is a chronic disease of the central nervous system, characterized by focal inflammatory lesions with demyelination and axonal loss. It is believed that MS is an immune-mediated disorder with both genetic and environmental contributions to the pathogenesis. LÄS MER