Sökning: "Multiphoton microscopy"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Multiphoton microscopy.

  1. 1. Multiphoton Microscopy Targeting Tissue Development. Towards the real-time imaging of epidermal differentiation

    Författare :Monika Malak; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; multiphoton microscopy; fluorescence lifetime imaging; epidermal differentiation; reconstructed human epidermis; organ-on-a-chip; intrinsic fluorescence;

    Sammanfattning : The development of novel organ-on-a-chip models calls for methodologies, which will allow the study of tissue development and pharmacological outcome in real-time. Multiphoton microscopy (MPM) has been proposed as a suitable technique for noninvasive imaging of live specimens, utilizing intrinsic tissue fluorescence. LÄS MER

  3. 2. Diagnostic aspects of skin cancer and lichen sclerosus studied with laser scanning microscopy

    Författare :Despoina Kantere; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; skin cancer; lichen sclerosus; reflactance confocal microscopy; multiphoton microscopy;

    Sammanfattning : Histopathologic examination of tissue biopsies is the current gold standard for the diagnosis of dermatological problems. Similarly, in oncology, sentinel lymph node (SLN) biopsy is the state-of-the-art diagnostic method for me- tastasis screening. LÄS MER

  4. 3. Multi-photon microscopy enhanced: Exploring annular beams and gold nano-particles for improved imaging

    Författare :Johan Borglin; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Multiphoton microscopy; Beam shaping; Gold nanoparticles;

    Sammanfattning : Laser scanning multiphoton microscopy (MPM) has emerged as a powerful tool for non-invasive three-dimensional imaging of biological tissue. The localized focal region enables confocality without the use of a physical pinhole while providing less photobleaching and photodamage compared to confocal laser scanning microscopy. LÄS MER

  5. 4. Non-linear Optical Microscopy and Spectroscopy for Biomedical Studies

    Författare :Stina Guldbrand; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Two-Photon Excitation Microscopy; Fluorescence Correlation Spectroscopy; Multiphoton Luminescence; Human Skin; Gold nanoparticles;

    Sammanfattning : This thesis is based on the application of non-linear optical microscopy and spectroscopy techniques within biomedical research. Non-linear optical microscopy gives the possibility of exciting fluorophores using near infrared light. LÄS MER

  7. 5. Laser Scanning Multiphoton Microscopy – Focusing on Fluorescence Correlation Spectroscopy and Fluorescence Lifetime Imaging for Biomedical Applications

    Författare :Jeemol James; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Laser scanning multiphoton microscopy; intrinsic cellular fluorophores.; fluorescence correlation spectroscopy; fluorescence lifetime imaging; melanoma metastasis;

    Sammanfattning : Laser scanning multiphoton microscopy (MPM) is considered as a non-invasive technology for three-dimensional imaging of complex biological tissues. The quantitative potential of the MPM is not investigated as much as qualitative imaging. LÄS MER