Avancerad sökning

Hittade 3 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Truncation and missing family links in population-based registers

    Författare :Monica Leu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Left-trunction; Swedish Cancer Registry; MultiGeneration Register; family history; misclassification; simulation; Poplab;

    Sammanfattning : Studies of familial aggregation of disease routinely use linked population registers to construct retrospective cohorts. Although such resources have provided numerous estimates of familial risk, little is known regarding the sensitivity of the estimates to assumed disease models and incompleteness of the data, such as truncation and/or missing family links. LÄS MER

  3. 2. Hemophagocytic lymphohistiocytosis and associations with malignancies

    Författare :Alexandra Haara Löfstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In immune homeostasis, natural killer cells and cytotoxic T cells are responsible for clearance of virus-infected and tumor transformed cells, but also for turning off the immune response. Patients with familial hemophagocytic lymphohistiocytosis (HLH) have impaired cytotoxic function due to genetic aberrations in genes in the perforindependent cytotoxic pathway. LÄS MER

  4. 3. Fertility in Inflammatory Bowel Disease

    Författare :Emma Druvefors; Pär Myrelid; Roland Andersson; Kalle Landerholm; Gunilla Sydsjö; Sonia Friedman; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ulcerative colitis; Crohn’s disease; Fertility; Ileal pouch anal anastomosis; Ileorectal anastomosis;

    Sammanfattning : Inflammatory bowel diseases (IBD) often present in adolescence or early adulthood and is thus frequently diagnosed in men and women in their reproductive age. Previous population-based studies of fertility in patients with IBD are scarce. LÄS MER