Sökning: "Muller cells"

Visar resultat 1 - 5 av 26 avhandlingar innehållade orden Muller cells.

  1. 1. Immune functions of intestinal dendritic cells

    Författare :Katarzyna Müller Luda; Slemhinnans immunologi; []
    Nyckelord :;

    Sammanfattning : The intestinal surface is daily challenged with tremendous amount of foreign material derived our diet and from the commensal bacteria that densely populate the mucosal surface. Occasionally the gut mucosa is exposed to pathogens trying to enter our body. LÄS MER

  3. 2. Hormonal regulation of HES-1 in breast cancer cells

    Författare :Patrick Müller; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hairy and Enhancer of Split homolog 1 (HES-1) is a transcriptional repressor belonging to the basic helix-loop-helix family of proteins, and has been shown to have a pivotal role as a regulator of neurogenesis, myogenesis and hematopoiesis. HES-1 has several well conserved domains, from Drosophila to mammals, and is expressed in a variety of tissues, in both embryos and adults. LÄS MER

  4. 3. Organic dust from pig environment induces activation of human T cells

    Författare :Charlotte Müller-Suur; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Organic dust; T cells; NK cells; cytokines; cellular activation;

    Sammanfattning : Farmers suffer more frequently from inflammatory airway disorders than the population in general and a ongoing airway inflammation has been shown also in symptom-free healthy farmers. Exposure in a swine confinement building causes an intense airway inflammation with recruitment of inflammatory cells, predominately neutrophils, in healthy, previously, non-exposed subjects. LÄS MER

  5. 4. Transcription factors regulating the Btk promoter

    Författare :Susanne Müller; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Btk; X-linked agammaglobulinemia; transcription factors; repression; synergism; Sp 1; Sp3; PU.l; Spi-B; genetherapy.;

    Sammanfattning : Bruton's agammaglobulinemia tyrosine kinase (Btk) is a cytoplasmic tyrosine kinase-related to the Src family of kinases. Mutations in various parts of the gene have been shown to lead to X-linked agammaglobulinemia, an immunodeficiency disease which is characterized by a defect in B-cell development. LÄS MER

  7. 5. Bringing order to disorder : structural and functional analysis for development of strategies to target MYC

    Författare :Inga Müller; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Several cellular processes such as cell cycle progression, apoptosis, cell adhesion and motility, cell growth, angiogenesis and differentiation are regulated by the MYC (here MYCN and c-MYC) proto-oncogenes. Elevated expression of MYC is present in a wide range of human tumors including Burkitt´s Lymphoma, neuroblastoma, medulloblastoma, colon cancer and glioblastoma. LÄS MER