Sökning: "Mukaiyama aldol"
Hittade 4 avhandlingar innehållade orden Mukaiyama aldol.
1. Natural Product Synthesis and Development of Novel Reaction Methodology
Sammanfattning : This thesis deals with the development of new reaction methodology for stereoselective synthesis, as well as total synthesis of natural products and investigations of the stereochemical outcome in the Mukaiyama aldol reaction. Chapter 2 describes efforts made towards the total synthesis of the oxindole natural products perophoramidine and the communesin. LÄS MER
2. Stereoselective Nucleophilic Additions to Aldehydes and Synthesis of α-Amino-β- Hydroxy-Esters
Sammanfattning : This thesis deals with the development of new reaction methodology as well as stereochemical investigations. The first part concerns the investigation of 1,2- and merged 1,2- and 1,3- asymmetric induction in Mukaiyama aldol additions to α-heteroatom and α,β- heteroatom substituted aldehydes respectively. LÄS MER
3. Stereoselective Nucleophilic Additions to α-Amino Aldehydes: Application to Natural Product Synthesis
Sammanfattning : This thesis deals with the development and application of new synthetic methodology for stereo- or regioselective construction of carbon-carbon bonds in organic synthesis. The first part of this thesis describes the development of a divergent protocol for stereoselective synthesis of chiral aminodiols by employing Mukaiyama aldol additions to syn- and anti-α-amino-β-silyloxy aldehydes. LÄS MER
4. Stereoselective Nucleophilic Additions to Aldehydes and Development of New Methodology in Organic Synthesis
Sammanfattning : This thesis is divided into four separate parts with nucleophilic addition to aldehydes as the common feature in three of them.The first part deals with the investigation of the stereochemical induction and elucidation of the factors that dictate the p-facial selectivities in Mukaiyama aldol addition to a- and a,b-heteroatom substituted aldehydes. LÄS MER
