Sökning: "Muhammad Waqas Sadiq"

Hittade 1 avhandling innehållade orden Muhammad Waqas Sadiq.

  1. 1. In Vivo Active Drug Uptake and Efflux at the Blood-Brain Barrier With Focus on Drug Transport Interactions

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Muhammad Waqas Sadiq; Uppsala universitet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; Active uptake transport; Microdialysis; P-glycoprotein; Drug interactions; Species differences; Pharmacokinetics; Pharmacodynamics; NONMEM; Pharmaceutical Science; Farmaceutisk vetenskap;

    Sammanfattning : The blood-brain barrier (BBB) controls the movement of substances into and out of the brain. The tight junctions between endothelial cells and energy dependent transporters in the BBB influence rate and extent of drug distribution to the brain. LÄS MER