Sökning: "Mucosal immunology"
Visar resultat 11 - 15 av 80 avhandlingar innehållade orden Mucosal immunology.
11. Dysregulated mucosal immune responses in microscopic colitis patients
Sammanfattning : Microscopic colitis (MC), comprising collagenous colitis (CC) and lymphocytic colitis (LC) is a common cause of chronic watery diarrhea. The diagnosis relies on typical histopathological changes observed upon microscopic examination. LÄS MER
12. T-cells in COPD to help or harm? A study of T-cells in COPD patients and related aspects of T-cell function in vitro
Sammanfattning : Chronic obstructive pulmonary disease, COPD, is manifested by chronic airflow limitation due to inflammation and tissue destruction in the lungs. COPD is caused primarily by smoking and with increasing cigarette consumption in the world, the prevalence for COPD will most probably increase in the future. LÄS MER
13. Functional analysis of the mouse J chain
Sammanfattning : We have in this study analyzed the function of the murine Joining chain (J chain) in vivo. J chain is a polypeptide found in sera and secretions in complex with pentameric IgM and dimeric IgA. LÄS MER
14. Does IgA play a role in protection against pulmonary tuberculosis?
Sammanfattning : More than a century after the identification of the tubercle bacillus and the first attempts at vaccination, tuberculosis (TB) still remains one of the world’s most serious infectious diseases. TB is typically a disease of the lung, which serves both as port of entry and as the major site of disease manifestation. LÄS MER
15. EFFECTOR T CELL HOMING TO THE SMALL INTESTINAL MUCOSA
Sammanfattning : The intestinal mucosa, including the intestinal epithelium and underlying lamina propria (LP), contains a large number of effector/memory T cells that are thought to play a central role in the generation and maintenance of mucosal immune responses and in maintaining mucosal integrity. The work in this thesis investigates the mechanisms regulating effector T cell recruitment to the small intestinal mucosa focusing on the role of chemokine receptors in this process. LÄS MER