Sökning: "Mucosa"

Visar resultat 11 - 15 av 540 avhandlingar innehållade ordet Mucosa.

  1. 11. Functional analysis of the mouse J chain

    Författare :Lena Erlandsson; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; diphtheria toxin A; plasma cell; mucosa; J chain; knock-out; serology; transplantation; Immunologi; serologi;

    Sammanfattning : We have in this study analyzed the function of the murine Joining chain (J chain) in vivo. J chain is a polypeptide found in sera and secretions in complex with pentameric IgM and dimeric IgA. LÄS MER

  3. 12. Expression and regulation of CCL25 and its role in T cell localization to and function within the small intestine

    Författare :Anna Ericsson; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosa; epithelium; intestine; transplantation; serology; Immunologi; Immunology; integrin; serologi; Chemokine;

    Sammanfattning : Earlier studies have demonstrated an important role for the chemokine CCL25, and its receptor CCR9, in the generation of the small intestinal lymphocyte compartment. The work in this thesis was aimed at determining how CCL25 is regulated within the small intestinal mucosa, and what potential role it plays in T cell localization to and function within this site. LÄS MER

  4. 13. On angiotensin II receptor type 2 receptors in the small intestine

    Författare :Sara Ewert; Göteborgs universitet; []
    Nyckelord :renin-angiotensin; angiotensin; small intestine; mucosa; epithelium; AT1; AT2; bradykinin; BK2 receptor; nitric oxide; iNOS; smooth muscle; contractility;

    Sammanfattning : The endocrine renin-angiotensin system (RAS) is important in the regulation of extracellular fluid volume and systemic blood pressure in strenuous conditions such as hypovolemia. Also present locally in peripheral tissues, all components of RAS are expressed and have been shown to modulate development, cell growth and inflammation. LÄS MER

  5. 14. Studies on the immuno-modulating properties of the cholera toxin A1-based fusion protein CTA1-DD

    Författare :Anna Eriksson; Göteborgs universitet; []
    Nyckelord :adjuvant; cholera toxin; mucosa; targeting; B cell; immuno-modulation; vaccine;

    Sammanfattning : The present work was aimed at exploring the immuno-modulating properties of the novel cholera toxin (CT)-based vaccine adjuvant CTA1-DD, which combines the full enzymatic activity of the A1 subunit of CT with B cell targeting. We have studied the efficacy of the CTA1-DD adjuvant to enhance immune responses in mice after nasal administration. LÄS MER

  7. 15. Involvement of the immune system in phytohaemagglutinin-induced structural and functional precocious maturation of the gut in young rats

    Författare :Olena Prykhodko; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytokines; mucosa; development; Gastrointestinal tract; mammals; immune system; T-cells;

    Sammanfattning : Mammals are born with an immature gastrointestinal (GI) tract that allows the uptake of the specific nutrients and bioactive macromolecules in the milk, especially the protecting maternal antibodies. Eventually during weaning, the intake of milk decreases while that of solid food increases, and the GI system undergoes prominent structural and functional changes adapting the young this dietary change. LÄS MER