Sökning: "MuRF1"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet MuRF1.

  1. 1. Protein expression and modifications in denervated atrophic and hypertrophic skeletal muscle

    Författare :Kim Evertsson; Sven Tågerud; Håkan Westerblad; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeletal muscle; denervation; atrophy; hypertrophy; protein expression; protein phosphorylation; Akt; p38; MK2; Hsp25; Hsp70; FoxO1; MuRF1; autophagy; Lamp1; Lc3; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : Skeletal muscle comprises about 45% of the total body weight. It is the largest tissue in the body, vital for maintaining posture, produce locomotion, breathing but also functions as a large reservoir of proteins. LÄS MER

  3. 2. The role of SUMO pathway in pathophsiology of skeletal muscle

    Författare :Arvind Venkat Namuduri; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Skeletal muscles are highly evolved and essential organs comprising 40 % of the total human body weight. They are essential in maintaining posture, energy metabolism, secrete hormones and act as central reserves for amino acids. LÄS MER

  4. 3. Old-age muscle atrophy : cellular mechanisms and behavioral consequenses

    Författare :Mikael Altun; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : With advancing age, humans and rodents alike lose about one third of the skeletal muscle mass. A process referred to as old-age muscle atrophy or sarcopenia. LÄS MER

  5. 4. Sarcopenia

    Författare :Erik Edström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Aging; sarcopenia; atrophy; regeneration; innervation; dietary restriction;

    Sammanfattning : Sarcopenia (Greek; sarcos: flesh, and penia: poverty) is the pronounced muscle loss that affects the aging population. Sareopenia of the leg muscles results in loss of independence and increased morbidity in the elderly. Emphasizing hind limb motor function, this thesis investigates different aspects of aging and sarcopenia in a rodent model. LÄS MER

  7. 5. Signaling factors related to atrophy and hypertrophy in denervated skeletal muscle

    Författare :Ann-Kristin Fjällström; Sven Tågerud; Jan Henriksson; Linnéuniversitetet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrophy; Hypertrophy; Skeletal muscle; Denervation; Protein synthesis; Protein degradation; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : The human body consists of about 40 % skeletal muscles which control the body’s movement, ability to stand up, force generation, locomotion, heat production and are also the body’s protein reservoir. Muscle mass is controlled by the relationship between protein synthesis and protein degradation. LÄS MER