Sökning: "Mouse fibroblasts"

Visar resultat 1 - 5 av 88 avhandlingar innehållade orden Mouse fibroblasts.

  1. 1. Regulation of mucosal inflammation by fibroblasts

    Författare :Tanya (De L.) Karlson; Göteborgs universitet; []
    Nyckelord :inflammatory bowel diseases; fibroblasts; CD40; C-EBPbeta; apoptosis; TGF-beta;

    Sammanfattning : ABSTRACT Acute inflammation in the bowel, a response of the immune system to infections or trauma, is probably a frequent but localized event, but when the barrier is repaired and the infection cleared, it is quickly followed by wound healing and resolution. However, in some individuals these mechanisms are not effective and the inflammatory bowel diseases, Crohn?s disease and ulcerative colitis result. LÄS MER

  3. 2. Osteotropic cytokines : expression in human gingival fibroblasts and effects on bone

    Författare :Py Palmqvist; Andersson Göran; Umeå universitet; []
    Nyckelord :osteoblasts; osteoclasts; fibroblasts; cytokines; IL-6; LIF; OSM; IL-4; IL-3; bone resorption; odontologi; Odontology;

    Sammanfattning : Bone metabolism is regulated by endocrine and paracrine signalling molecules influencing bone cells in the continuously remodelling bone tissue. These molecules include a variety of osteotropic stimulatory and inhibitory cytokines. LÄS MER

  4. 3. About hyaluronan in the hypertrophic heart : studies on coordinated regulation of extracellular matrix signalling

    Författare :Urban Hellman; Anders Waldenström; Stellan Mörner; Anna Engström-Laurent; Lena Jonasson; Umeå universitet; []
    Nyckelord :hyaluronan; hyaluronan synthases; gene expression; extracellular matrix; cardiac hypertrophy; rat wistar; male ; cardiomyocytes; growth factors; fibroblasts; microvesicles; exosomes; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Background. Myocardial hypertrophy is a risk factor for cardiovascular morbidity and mortality. Independent of underlying disease, the cardiac muscle strives in different ways to compensate for an increased workload. This remodelling of the heart includes changes in the extracellular matrix which will affect systolic and diastolic cardiac function. LÄS MER

  5. 4. The role of the adventitia and perivascular tissue for the formation of intimal hyperplasia

    Författare :Per Fogelstrand; Göteborgs universitet; []
    Nyckelord :Intimal hyperplasia; adventitia; perivascular tissue; smooth muscle cells; fibroblasts; balloon injury; vein graft; artificial graft;

    Sammanfattning : Symptomatic atherosclerosis is commonly treated with balloon angioplasty or bypass surgery. About 30% of the interventions will re-narrow within a year due to restenosis and graft-stenosis. Thickening of the luminal layer, the intima, is an important component in these side-effects. LÄS MER

  7. 5. Studies on the antiproliferative action of interferon : effects on proteins synthesized in the G1 and S phase of the cell cycle in 2 anchorage-dependent cell lines

    Författare :Dan Lundblad; Erik Lundgren; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Interferon; Glioma; Antiproliferative effect; DNA polymerase; Thymidine kinase; 2 -5 oligo A; Protein synthesis; Two-dimensional electrophorensis; Mouse fibroblasts; C-myc; KI-67 antigen;

    Sammanfattning : Interferons (IFNs) are a class of structurally related proteins first discovered to be produced by virus-infected cells. By now, several other inducing agents have been described. LÄS MER