Sökning: "Monocytes"
Visar resultat 21 - 25 av 375 avhandlingar innehållade ordet Monocytes.
21. Molecular and cellular interactions on noble metal nanopatterned surfaces − applications towards bone, soft tissue and infection control
Sammanfattning : Biomaterial-associated infection is recognised as one of the main risks for failure of medical devices. The presence of a foreign material in tissues has been suggested to compromise the ability of host cells to eradicate infection. LÄS MER
22. Regulation of tissue factor expression in myeloid and monocytic leukaemia cells
Sammanfattning : Tissue factor (TF) is a transmembrane glycoprotein that initiates the blood coagulation cascade and is also involved in cell migration, tumour metastasis and angiogenesis. Pathologic expression of tissue factor by monocytes contributes to several thrombotic complications like acute coronary artery disease and disseminated intravascular coagulation. LÄS MER
23. It Takes Two to Tango : Bacterial heterogeneity and host cell features govern Salmonella infection
Sammanfattning : Salmonella enterica serovar Typhimurium (S.Tm) causes enterocolitis with significant worldwide morbidity and mortality. The general aim of this thesis is to investigate variation in host cell invasion mechanisms used by S.Tm across different host cell contexts, as well as the influence of bacterial cell-cell heterogeneity on invasion-relevant S. LÄS MER
24. The role of myeloid cells in neurodegenerative diseases. Studies on cellular phenotype and communication
Sammanfattning : Neurological disorders are listed as the second leading cause of death worldwide. Stroke and Alzheimer’s disease (AD) are the major contributors to neurological disorders of deaths. Every year, around 14 million new people are affected by stoke and nearly 10 million new cases of AD are diagonosed worldwide. LÄS MER
25. Infective Endocarditis : aspects of pathophysiology, epidemiology, management and prognosis
Sammanfattning : Infective endocarditis (IE) is a rare but complex disease that is fatal if untreated. With a modern combination of antimicrobial therapy and heart valve surgery, mortality is still 10-20 %. The structure of the endocarditis vegetation impedes the penetration of phagocytic cells such as monocytes and granulocytes. LÄS MER