Sökning: "Monika"

Visar resultat 6 - 10 av 144 avhandlingar innehållade ordet Monika.

  1. 6. Activation of the novel PDGFS by plasminogen activators in tumorigenesis

    Författare :Monika Ehnman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Members of the platelet-derived growth factor (PDGF) family are mitogens for cells of a mesenchymal origin and have important functions both during development and in the adult. Their role in developmental processes has been extensively investigated by methodical targeted gene inactivations, revealing critical involvement in microvascular pericyte recruitment, neural crest development and alveogenesis. LÄS MER

  3. 7. Sickness certification when experienced as problematic by physicians

    Författare :Monika Engblom; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :sick leave;

    Sammanfattning : Background and aim: Physicians play an essential role in the sickness absence process, and many of them experience related tasks as problematic. The overall aim of this thesis was to improve the understanding of sickness certification experienced as problematic by physicians in general practice and occupational health services, and to gain more knowledge about the frequency and severity of those problems. LÄS MER

  4. 8. Mechanisms influencing natural killer cell recognition of tumour cells

    Författare :Monika Enqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Natural killer (NK) cells are part of our innate immune defence against virus-infected and transformed cells. Through a yet undefined mechanism, expression of inhibitory receptors for self-HLA class I molecules endow NK cells with increased functionality. The process leading to gain of function through inhibition is known as NK cell education. LÄS MER

  5. 9. The impact of transcriptional mutagenesis on cellular homeostasis

    Författare :Monika Ezerskyte; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : DNA is exposed to chemical and physical agents that represent a continuous threat to its integrity by formation of DNA lesions. Despite the existence and efficiency of DNA repair systems in cells, some lesions may not be removed, and interfere not only with the fidelity of DNA replication but also with DNA transcription. LÄS MER

  7. 10. Environmental Risk Assessment - Uncertainty, variability and statistical methods

    Författare :Monika Filipsson; School of Pure and Applied Natural Sciences University of Kalmar; []
    Nyckelord :Miljövetenskap; Environmental Science;

    Sammanfattning : .... LÄS MER