Sökning: "Molekylär genetik"
Visar resultat 11 - 15 av 126 avhandlingar innehållade orden Molekylär genetik.
11. Evolution of symbiotic lineages and the origin of new traits
Sammanfattning : This thesis focuses on the genomic study of symbionts of two different groups of hymenopterans: bees and ants. Both groups of insects have major ecological impact, and investigating their microbiomes increases our understanding of their health, diversity and evolution. LÄS MER
12. Functional Significance of Multiple Poly(A) Polymerases (PAPs)
Sammanfattning : 3’ end cleavage and polyadenylation are important steps in the maturation of eukaryotic mRNAs. Poly(A) polymerase (PAP), the enzyme catalysing the addition of adenosine residues, exists in multiple isoforms. In this study the functional significance of multiple poly(A) polymerases have been investigated. LÄS MER
13. Genetic Variation and Expression of the IRF5 Gene in Autoimmune Diseases
Sammanfattning : The interferon regulatory factor 5 (IRF5) gene encodes a transcription factor that plays an important role in the innate as well as in the cell-mediated immune response. The IRF5 gene has received considerable attention since it was shown to be associated with two autoimmune diseases; systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). LÄS MER
14. Endothelial differentiation and angiogenesis regulation
Sammanfattning : Angiogenesis can be defined as the formation of new blood vessels from pre-existing ones. Angiogenesis is required for development and maintenance of our vascular system and thus of fundamental importance to our existence. LÄS MER
15. Extracting Genomic Variations using Selector Technology
Sammanfattning : This thesis describes the development and use of a new class of molecular tools called Selector probes, and its potential for investigations of genetic variation. The Selector technology provides multiplex amplification of targeted DNA sequences with a high specificity, and an enrichment factor in the same order of magnitude as PCR. LÄS MER