Sökning: "Mitochondrial DNA"

Visar resultat 21 - 25 av 262 avhandlingar innehållade orden Mitochondrial DNA.

  1. 21. Molecular and structural studies of proteins required for mitochondrial DNA maintenance

    Författare :Carlos Pardo-Hernandez; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mtDNA; LONP1; POLγ; mtDNA maintenance; mitochondrial disease; TWINKLE; mitochondria;

    Sammanfattning : Mitochondria are membrane-bound organelles that produce the majority of ATP used to drive metabolic processes in eukaryotic cells. A unique feature of mitochondria is the existence of a separate mitochondrial DNA (mtDNA), which codes for thirteen proteins needed for oxidative phosphorylation (OXPHOS). LÄS MER

  3. 22. A new perspective on avian phylogeny - a study based on mitochondrial genomes

    Författare :Anna Bartosch-Härlid; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; thyroid; neoteni; mitochondrial DNA; phylogeny; Class Aves; Palaeognathae; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : The Class Aves (birds) is generally divided into two main groups - the Palaeognathae and the Neognathae. Paleognathous birds are the flightless ratites and the tinamous, while Neognathae include all other extant birds (more than 9,000 species). LÄS MER

  4. 23. Cell-Penetrating Peptides for Mitochondrial Targeting

    Författare :Carmine Pasquale Cerrato; Ülo Langel; Shana O. Kelley; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondrial targeting; cell-penetrating peptides; antioxidant activity; scavenging ability; oligonucleotide delivery; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Mitochondria have simply been known as the cell’s powerhouse for a long time, with its vital function of producing ATP. However, substantially more attention was directed towards these organelles once they were recognized to perform several essential functions having an impact in cell biology, pharmaceutics and medicine. LÄS MER

  5. 24. The evolution of flat periwinkles Littorina fabalis and L. obtusata emhasizing mitochondrial introgression and restricted recombination

    Författare :Petri Kemppainen; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Speciation; Local adaptations; Ecotypes; Mitochondrial DNA; Introgression; Restricted recombination; Positive selection; Inversions; Chromosomal rearrangements;

    Sammanfattning : The evolution of species takes in general very long time and different mechanisms are likely to operate during the various stages of this process. Accordingly speciation should be studied at different levels of species divergence. LÄS MER

  7. 25. Molecular mechanisms of mammalian mitochondrial DNA replication and transcription

    Författare :Mina Pellegrini; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mitochondrion; DNA polymerase gamma; mtSSB; TWINKLE; DNA replication; transcription; mTERF; MTERF3; MTERF2; nucleoid;

    Sammanfattning : Mitochondria are cytoplasmic organelles in eukaryotic cells, mainly devoted to the synthesis of ATP, through the Oxydative Phospshorylation System (OXPHOS). The organelle has its own genome, the mitochondrial DNA (mtDNA) that encodes for all the RNA components of the mitochondrial translation apparatus (two rRNAs and 22 tRNAs) and for 13 subunits of the OXPHOS complexes. LÄS MER