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Sammanfattning : Prenatal nicotine exposure (such as from maternal smoking during pregnancy) has been hypothesized to cause a so called programming effect, where epigenetic changes might result in a long-lasting vulnerability to tobacco use and dependence, manifesting during adolescence or young adulthood. However, previous observational studies show mixed results, perhaps because the association could be influenced by a common genetic predisposition to tobacco use as well as by social factors influencing both parental tobacco use during pregnancy and tobacco use in the offspring. LÄS MER