Sökning: "Mina Pellegrini"

Hittade 1 avhandling innehållade orden Mina Pellegrini.

1. 1. Molecular mechanisms of mammalian mitochondrial DNA replication and transcription

   Författare :Mina Pellegrini; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Mitochondrion; DNA polymerase gamma; mtSSB; TWINKLE; DNA replication; transcription; mTERF; MTERF3; MTERF2; nucleoid;

   Sammanfattning : Mitochondria are cytoplasmic organelles in eukaryotic cells, mainly devoted to the synthesis of ATP, through the Oxydative Phospshorylation System (OXPHOS). The organelle has its own genome, the mitochondrial DNA (mtDNA) that encodes for all the RNA components of the mitochondrial translation apparatus (two rRNAs and 22 tRNAs) and for 13 subunits of the OXPHOS complexes. LÄS MER