Avancerad sökning

Hittade 2 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Telomeres and the brain : an investigation into the relationships of leukocyte telomere length with functional and structural attributes of the brain

   Författare :Mikael Wikgren; Karl-Fredrik Norrback; Rolf Adolfsson; Göran Roos; Thomas Karlsson; Brenda Penninx; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; APOE; aging; atrophy; brain; cognition; cortisol; depression; hippocampus; HPA axis; MRI; stress; telomere length; white matter hyper-intensities.;

   Sammanfattning : Telomeres are the outermost parts of linear chromosomes. They consist of tandemly repeated non-coding short nucleotide sequences (TTAGGG in all vertebrates), in humans spanning over the last 2 to 15 kilobase pairs of the chromosome. Due to the end-replication problem, telomeres shorten with each cellular division. LÄS MER

3. 2. Hypocortisolism in recurrent affective disorders

   Författare :Martin Maripuu; Karl-Fredrik Norrback; Rolf Adolfsson; Mikael Wikgren; Marie Åsberg; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affective disorders; Bipolar disorder; Cortisol; Depression; HPA-axis; Hypercortisolism; Hypocortisolism; Lithium; Metabolic syndrome; Obesity; Quality of life; Recurrent depression; Stress; Telomeres;

   Sammanfattning : Bipolar disorders and recurrent depressions are two common psychiatric disorders with a life time prevalence of approximately 1% and 8%, respectively. Despite treatment these patients suffer from affective symptoms up to 50% of the time, resulting in lower well-being. LÄS MER