Sökning: "Micronuclei"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet Micronuclei.

  1. 1. Cancer Risk Assessment of Glycidol : Evaluation of a Multiplicative Risk Model for Genotoxic Compounds

    Författare :Jenny Aasa; Margareta Törnqvist; Elaine M. Faustman; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; glycidol; 3-monochloropropane-1; 2-diol 3-MCPD ; genotoxicity; mutations; micronuclei; hemoglobin adducts; in vivo dose; multiplicative risk model; cancer risk assessment; human cancer risk; miljökemi; Environmental Chemistry;

    Sammanfattning : Humans are exposed to chemical compounds in everyday life, both from the environment and from endogenous processes. Some compounds constitute a risk for cancer development. One such compound is glycidol, which is genotoxic and an animal carcinogen. It is the model compound of this work, partly due to its presence in food. LÄS MER

  2. 2. On computational methods for spatial mapping of thehuman proteome

    Författare :Casper F. Winsnes; Emma Lundberg; Ida-Maria Sintorn; KTH; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Spatial proteomics; Human Protein Atlas; Micronuclei; Citizen science; Biotechnology; Bioteknologi;

    Sammanfattning : Proteins are complex molecules that are involved in almost every task in the body. In general, the role a protein fulfills is highly dependent on where in the cell it is located, its subcellular localization. LÄS MER

  3. 3. In vitro radiobiological effects of 131I on thyroid cells: towards a mechanistic understanding of thyroid stunning

    Författare :Nirmal Bhogal; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :thyroid; radioiodide; stunning; 131I; stress response; DNA damage; Chk2; H2AX; micronuclei; cell cycle;

    Sammanfattning : .... LÄS MER

  4. 4. Cellular effects after exposure to mixed beams of ionizing radiation

    Författare :Elina Staaf; Andrzej Wojcik; Siamak Haghdoost; Eva Forssell-Aronsson; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Ionizing radiation; high LET; low LET; mixed beams; combined exposure; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Mixed beams of ionizing radiation in our environment originate from space, the bedrock and our own houses. Radiotherapy patients treated with boron neutron capture therapy or with high energy photons are also exposed to mixed beams of gamma radiation and neutrons. LÄS MER

  5. 5. Chemometrics : Unravelling information from complex data generated by modern instruments

    Författare :Pedro F. M. de Sousa; Magnus Åberg; Johan Trygg; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Chemometrics; Chromatography; Mass spectrometry; DIA; PCA; PLS; Experimental Design; DNA; adductomics; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Chemometrics is a discipline dedicated to solving problems arising from complicated analytical systems, combining statistics, mathematics, and computational programming languages.This thesis is based on the work developed in four scientific projects published as papers in scientific journals. LÄS MER