Sökning: "Microfluidic"

Visar resultat 6 - 10 av 206 avhandlingar innehållade ordet Microfluidic.

  1. 6. Compact-disc microfluidic methods for characterization of therapeutic antibodies : Analysis of post-translational modifications

    Författare :Thi Thuy Tran; Gunnar Thorsén; McLean John; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microfluidic CD; therapeutic antibodies; post-translational modifications; glycosylation profiling; multivariate statistical analysis; MALDI-MS; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Characterization of post-translational modifications (PTMs) of therapeutic proteins is very important during the bioprocess development to maintain desired product quality and during the submission process to regulatory authorities for product approval. Monitoring glycosylation in pharmacokinetic studies can be useful to evaluate the dependence of clearance rates on different glycoforms. LÄS MER

  3. 7. Capillary driven devices for patient-centric diagnostics

    Författare :Gabriel Lenk; Niclas Roxhed; Göran Stemme; Jens Ducrée; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Capillary driven; Microfluidic; Dissolvable valves; PVA; Volume metering; Dried Blood Spots; DBS; Dried Plasma Spots; DPS; Medicinsk teknologi; Medical Technology;

    Sammanfattning : Lateral flow assays is an example of a successful microfluidic platform relying on passive fluid transport, making them suitable for patient-centric and point-of-care applications. Flow control and valving in capillary driven devices typically rely on design-imprinted functions and operations which can be a limiting factor. LÄS MER

  4. 8. Single Molecule Detection : Microfluidic Automation and Digital Quantification

    Författare :Malte Kühnemund; Mats Nilsson; Ulf Landegren; Sten Linnarsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single molecule; digital; rolling circle amplification; magnetic particle; padlock probe; microfluidics; resistive pulse sensing; lab on chip; mobile phone microscopy; enrichment; sequencing;

    Sammanfattning : Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, which now permit the detection and analysis of single molecules with high sensitivity and specificity. Assay sensitivity is fundamentally limited by the efficiency of the detection method used for read-out. LÄS MER

  5. 9. Thermoplasmonic Effects in Microfluidic Systems

    Författare :Steven Jones; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; thermometry; thermoplasmonic bubbles; thermoplasmonics; plasmonics; thermophoresis;

    Sammanfattning : The field of plasmonics has enabled a plethora of scientific achievements over the past few decades. Such advances have been the result of the increased light-matter interaction that occurs over nanoscale dimensions facilitated by the localized plasmonic resonances supported by noble metal nanoparticles. LÄS MER

  7. 10. Paraffin Actuators in Microfluidic Systems

    Författare :Marcus Lehto; Klas Hjort; Peter Woias; Uppsala universitet; []
    Nyckelord :Engineering physics; Paraffin; Actuators; Valve; Micropump; Teknisk fysik;

    Sammanfattning : There is a need for reliable valves and pumps in microfluidics. A good microactuator is the key for low cost and high performance of these components.Paraffin wax is a promising material to be used as actuator material as is can produce large forces and large strokes. LÄS MER