Sökning: "Microfluidic system"

Visar resultat 16 - 20 av 109 avhandlingar innehållade orden Microfluidic system.

  1. 16. Optical manipulation and spectroscopy of single functional globin-containing cells in microfluidic systems

    Författare :Kerstin Ramser; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; heme-proteins; optical manipulation; resonance Raman spectroscopy; microfluidic systems; single cells; Medical Engineering for Healthcare;

    Sammanfattning : Recent advances in microbiology and biomedicine require development of tools to monitor the response of single cells to environmental stimuli under controlled physiological conditions. In this thesis, I describe how this can be achieved by combining various spectroscopic techniques with optical tweezers and microfluidic systems. LÄS MER

  2. 17. Silicon Nanoribbon FET Sensors : Fabrication, Surface Modification and Microfluidic Integration

    Författare :Roodabeh Afrasiabi; Jan Linnros; Michel Calame; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Informations- och kommunikationsteknik; Information and Communication Technology;

    Sammanfattning : Over the past decade, the field of medical diagnostics has seen an incredible amount of research towards the integration of one-dimensional nanostructures such as carbon nanotubes, metallic and semiconducting nanowires and nanoribbons for a variety of bio-applications. Among the mentioned one-dimensional structures, silicon nanoribbon (SiNR) field-effect transistors (FET) as electro-chemical nanosensors hold particular promise for label-free, real-time and sensitive detection of biomolecules using affinity-based detection. LÄS MER

  3. 18. Novel Microfluidic Devices Based on a Thermally Responsive PDMS Composite

    Författare :Björn Samel; Göran Stemme; Jörg Kutter; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEMS; microsystem technology; micro total analysis system; lab-on-a-chip; microfluidics; composite actuator; expandable microspheres; PDMS; poly dimethylsiloxane; disposable; wafer bonding; adhesive bonding; PDMS bonding; adhesive PDMS bonding; selective PDMS bonding; microcontact printing; Electrical engineering; Elektroteknik;

    Sammanfattning : The field of micro total analysis systems (μTAS) aims at developments toward miniaturized and fully integrated lab-on-a-chip systems for applications, such as drug screening, drug delivery, cellular assays, protein analysis, genomic analysis and handheld point-of-care diagnostics. Such systems offer to dramatically reduce liquid sample and reagent quantities, increase sensitivity as well as speed of analysis and facilitate portable systems via the integration of components such as pumps, valves, mixers, separation units, reactors and detectors. LÄS MER

  4. 19. Microfluidic and Molecular Tools for Genetic Analyses

    Författare :Henrik Johansson; Mats Nilsson; Ivo Gut; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microfluidics; PCR; sequencing; cancer genetics; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Medical Genetics; Medicinsk genetik;

    Sammanfattning : Methods that enable interrogation of multiple genomic regions in parallel are very useful for efficient detection of genetic variation. Two different types of probes are described in this thesis that can be used for direct analysis or for sample preparation upstream of Next Generation Sequencing. LÄS MER

  5. 20. Miniaturized fluid system for high-pressure analytics

    Författare :Simon Södergren; Klas Hjort; Sami Franssila; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; High-pressure; Microfluidics; Thermal regulation; Fluid mechanics; In-situ sensors; High-pressure analytics; Teknisk fysik med inriktning mot mikrosystemteknik; Engineering Science with specialization in Microsystems Technology;

    Sammanfattning : High-pressure chemistry can be used to determine the contents of blood or water samples and to discover new chemistries. However, working with chemistry at pressures of many tens, or even hundreds, of bars often requires expensive and stationary equipment, such as autoclaves or chromatographic systems like high-performance liquid chromatography (HPLC). LÄS MER