Sökning: "Michael Holers"
Hittade 1 avhandling innehållade orden Michael Holers.
1. IgM and Complement in Regulation of Antibody Responses
Sammanfattning : Animals deficient in complement components C1q, C4, C3, and CR1/2 have severely impaired antibody responses. C1q is primarily activated by antibody-antigen complexes. Antigen-specific IgM in complex with an antigen is able to enhance the antibody response against that antigen. This is dependent on the ability of IgM to activate complement. LÄS MER
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