Sökning: "Mice"

Visar resultat 16 - 20 av 2577 avhandlingar innehållade ordet Mice.

1. 16. The B lymphocyte in Staphylococcus aureus arthritis

   Författare :Inger Gjertsson; Göteborgs universitet; []
   Nyckelord :Staphylococcus aureus; mice; arthritis; sepsis; B cells; Fcg receptors; CD22; ; IL-4; IL-10; IFN-g.;

   Sammanfattning : Joint infection caused by Staphylococcus aureus leads to heavy synovitis and rapid destruction of bone and cartilage. Permanent loss of joint function is seen in 20-50% of the patients, despite early eradication of the bacteria with antibiotics. LÄS MER

3. 17. Helicobacter pylori infection in a mouse model: Development, optimization and inhibitory effects of antioxidants

   Författare :Xin Wang; Avdelningen för medicinsk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; virology; bacteriology; Microbiology; mice; Helicobacter pylori; gastritis; lymphoma; antioxidant; diet; Th1 and Th2; cytokines; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : Helicobacter pylori is a human pathogen strongly associated with chronic type B gastritis, peptic ulcer disease, gastric cancer and MALT lymphoma. Our aims were to establish a mouse model of H. pylori infection, to study pathogenesis of gastritis and gastric cancer and to investigate new treatment strategies in this model. LÄS MER

4. 18. Mycobacterial infection: Immune evasion, host susceptibility and immunological markers of diagnostic importance

   Författare :John Arko-Mensah; Carmen Fernandez; Francesco Dieli; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacteria; Mice; Toll-like receptors; interferon gamma; immunological markers; lung; respiratory tract; susceptibility; Immunology; Immunologi; immunologi; Immunology;

   Sammanfattning : IIn the first study, we investigated the functional implications of prolonged TLR signalling on IFN-γ mediated killing of mycobacteria by murine macrophages in vitro. TLR2, but not TLR4 ligation interfered with IFN-γ mediated killing of mycobacteria in macrophages. LÄS MER

5. 19. Host-bacterium relationship in staphylococcal skin infection

   Författare :Lena Mölne; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Staphylococcus aureus; skin; mice; superantigen; TSST-1; neutrophils; gamma delta T cells; bacterial DNA; CpG ODN;

   Sammanfattning : Skin infections caused by Staphylococcus aureus are commonly occuring, both in the community and in hospitals. Despite the high prevalence of this condition, little is known about the host immune responsiveness and bacterial virulence factors during S. aureus skin infection. LÄS MER

7. 20. Localization of lipoprotein lipase in mouse pancreas, kidney and placenta : impact of metabolic disturbances on cellular distribution and activity regulation

   Författare :Rakel Nyrén; Gunilla Olivecrona; Paolo Parini; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipoprotein lipase; pancreas; kidney; placenta; angiopoietin-like protein 4; high-fat diet; obesity; mice; PET CT; nutritional status; triglyceride; GPIHBP1; medicinsk och fysiologisk kemi; Medical and Physiological Chemistry;

   Sammanfattning : Lipoprotein lipase (LPL) is the key enzyme for metabolism of triglycerides in plasma lipoproteins. In recent years many new facts about the enzyme and its regulation have been uncovered. The endothelial membrane protein GPIHBP1 translocates LPL through endothelial cells and holds the enzyme in place at the luminal side of the capillary endothelium. LÄS MER