Sökning: "Mhc class II B"

Visar resultat 1 - 5 av 78 avhandlingar innehållade orden Mhc class II B.

  1. 1. Genetic Variation in Mhc Class II B in Atlantic Salmon: Evolutionary and Ecological Perspectives

    Författare :Åsa Langefors; Biodiversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; recombination; genetic variation; Mhc class II B; Atlantic salmon; evolution; population genetics; Animal ecology; Djurekologi;

    Sammanfattning : The Major Histocompatibility Complex (Mhc) genes are crucial for the recognition of self and non-self peptides by the immune defence system. They are extremely variable in most studied vertebrate species. I have studied the extent and the importance of Mhc variation in Atlantic salmon (Salmo salar), mainly from the Baltic Sea. LÄS MER

  3. 2. The Germinal Centre reaction - Genetic and proteomic analysis of factors important for survival and growth of B lymphocytes

    Författare :Linda Zander; Göteborgs universitet; []
    Nyckelord :B lymphocyte; germinal centre; transformation; serum-free; MHC class II; bare lymphocyte syndrome; extracellular proteins; DNA repair; Polymerase ?;

    Sammanfattning : During an immune response the B lymphocytes main function is to produce antibodies in the specific defence against the pathogen. When naïve B lymphocytes become activated by binding of an antigen, the cells differentiate to become antibody producing plasma cells. LÄS MER

  4. 3. MHC and Transgenic Mice. A study into polymorphism and function of class I and class II molecules

    Författare :Mikael Vestberg; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MHC rat mouse transgenic autoimmunity collagen peptide; Clinical biology; Klinisk biologi;

    Sammanfattning : Transplantation antigens encoded in the major histocompatibility complex (MHC) bind peptides and present them to T cells. We showed that mouse T cells expressing transgenic human CD8 can recognise human MHC class I. LÄS MER

  5. 4. Molecular basis for the MHC class II association in rat experimental autoimmune encephalomyelitis

    Författare :Katrien L de Graaf; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis investigates the functional and structural aspects of rat MHC class 11 molecules and studies their influence on MBP- and MOG-peptide induced experimental autoimmune encephalomylitis (EAE) in LEW MHC congenic rat strains. EAE is an animal model for multiple sclerosis (MS) and can be induced in rats with components of the myelin sheath . LÄS MER

  7. 5. Staphylococcal enterotoxin H - structure and function of a superantigen

    Författare :Helen Pettersson; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; TCR; staphylococcal enterotoxin H; MHC class II; superantigen; transplantation; Immunologi; serologi; serology;

    Sammanfattning : The aim of this thesis was to characterise the biological functions of the superantigen staphylococcal enterotoxin H (SEH). Superantigens are highly immunostimulatory proteins, which crosslink T cells and antigen presenting cells (APCs). LÄS MER