Sökning: "Method Validation"

Visar resultat 1 - 5 av 682 avhandlingar innehållade orden Method Validation.

  1. 1. Drug Analysis : Bioanalytical Method Development and Validation

    Författare :Mikaela Malm; Yngve Bergqvist; Anders Colmsjö; Uppsala universitet; []
    Nyckelord :Analytical chemistry; African trypanosomiasis; calibration model; chiral chromatography; dried blood spots; eflornithine; evaporative light-scattering detection; HIV AIDS; lamivudine; liquid chromatography; malaria; nevirapine; piperaquine; pneumonia; solid-phase extraction; sulfadoxine; sulfamethoxazole; validation; zidovudine; Analytisk kemi;

    Sammanfattning : This thesis describes bioanalytical methods for drug determination in biological matrixes, with drugs in focus used against diseases largely affecting low-income countries. Solid-phase extraction is used for sample cleanup, and processed samples are analyzed by liquid chromatography. LÄS MER

  2. 2. Förhållningssätt och kommunikation i mötet med personer med demenssjukdom : utvärdering av ett träningsprogram med validationsmetoden

    Författare :Mona Söderlund; Görel Hansebo; Astrid Norberg; Britt-Marie Ternestedt; Agneta Cronqvist; Helle Wijk; Ersta Sköndal högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Validation method; Evaluation studies; Dementia care; Communication skills; Caring approach; Videotaped conversations; Qualitative analyses; validation method;

    Sammanfattning : Communication difficulties among residents with dementia disease living in nursing homes may complicate care situations. These residents can have difficulties describing how they experience their everyday lives, which can lead to withdrawal, social isolation, or feelings of homelessness. LÄS MER

  3. 3. Development and Validation of HPLC Methods for Analytical and Preparative Purposes

    Författare :Johan Lindholm; Torgny Fornstedt; Karin Caldwell; Karl-Gustaf Wahlund; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; High performance liquid chromatography HPLC ; Analytical biotechnology; Sample preparation; Diode-array-detection DAD ; Mass spectrometry MS ; Validation; Preparative chromatography; Competitive isotherm parameters; Perturbation peak PP method; Kemi; Chemistry; Kemi;

    Sammanfattning : This thesis concerns the development and validation of high performance liquid chromatography (HPLC) methods aimed for two industrially important areas: (i) analysis of biotechnological synthesis and (ii) determination of adsorption isotherm parameters. There is today a lack of detailed recommendations for analytical procedures in the field of biotechnological production of drugs. LÄS MER

  4. 4. Optimization and Model Validation of Transonic Compressors

    Författare :Lars R Ellbrant; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; compressor; optimization; design; metamodels; CFD; validation; multiobjective;

    Sammanfattning : Economical aspects such as reduced specific fuel consumptions and ever growing environmental requirements on emissions and percieved noise levels, are the major drivers in the search for improvement of aircraft engines. For turbofan engines, the global trend is towards higher efficiency which is accomplished by increasing component efficiencies, the bypass ratio and overall pressure ratio while keeping the engine weight low. LÄS MER

  5. 5. Simulation of welding and heat treatment : modelling and validation

    Författare :Henrik Alberg; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Datorstödd maskinkonstruktion; Computer Aided Design;

    Sammanfattning : Many aerospace components with complex geometry are fabricated from smaller parts using joining techniques such as welding. Welding and the heat treatment which usually follows, can result in unwanted deformation and stresses. LÄS MER