Sökning: "Metastatic breast cancer"
Visar resultat 11 - 15 av 90 avhandlingar innehållade orden Metastatic breast cancer.
11. Growth factor signaling in the breast tumor microenvironment
Sammanfattning : Cancer represents a collection of malignancies characterized by an aberrant expansion of cells. This unrestrained growth is the result of the acquisition of several pro-survival features and the evasion of cellular fail-safe mechanisms, collectively known as the hallmarks of cancer. LÄS MER
12. Role of DARPP-32 in Breast Cancer Cell Signalling and Migration
Sammanfattning : Breast cancer is the most common form of cancer in women. While the prognosis for breast cancer patients without local or distal dissemination is relatively favorable, the prognosis is considerably worse once distal metastasis has been established. LÄS MER
13. Breast Cancer Biomarkers with Clinical Relevance Identified by Massively-parallel DNA and RNA Sequencing
Sammanfattning : Women have a 10% lifetime risk of developing breast cancer, and the disease has surpassed lung cancer as the most frequently diagnosed type of cancer in the world. Breast cancer originates in the epithelial cells of the mammary gland and tumor cells have undergone a series of genetic and phenotypic changes that confer tumor promoting properties. LÄS MER
14. Translational Aspects of Erythropoietin Receptor and Hypoxia-Inducible Factors in Breast Cancer
Sammanfattning : The main function of erythropoietin (EPO) is in hematopoiesis where EPO stimulates increased proliferation, survival and differentiation of erythrocytic precursors in response to hypoxia. The EPO effect is mediated via binding to the EPO receptor (EPOR), which induces activation of different intracellular signaling pathways. LÄS MER
15. Multiple primary malignancies in breast cancer patients. From population study to genetics
Sammanfattning : Breast cancer (BC) is one of the most common causes of cancer-related death among women worldwide. Due to early detection of BC and more tailor-made treatments, patients live longer despite their illness. Studies have shown that BC patients are at risk of developing new tumors in organs other than the breast, mainly caused by BC treatment. LÄS MER