Sökning: "Metagenomics"

Visar resultat 16 - 20 av 64 avhandlingar innehållade ordet Metagenomics.

  1. 16. Exploration of microbial diversity and evolution through cultivation independent phylogenomics

    Författare :Joran Martijn; Thijs J.G. Ettema; Andrew Roger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cultivation independent genomics; metagenomics; single-cell genomics; metagenomic binning; phylogenetics; phylogenomics; phylogenetic artefacts; comparative genomics; gene tree-species tree reconciliation; rRNA amplicon sequencing; Tara Oceans; origin of mitochondria; Alphaproteobacteria; Rickettsiales; Haloarchaea; endosymbiosis; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : Our understanding of microbial evolution is largely dependent on available genomic data of diverse organisms. Yet, genome-sequencing efforts have mostly ignored the diverse uncultivable majority in favor of cultivable and sociologically relevant organisms. LÄS MER

  3. 17. Evolution of streamlined genomes in ultra-small aquatic bacteria

    Författare :Weizhou Zhao; Siv Andersson; Sandra L. Baldauf; Sarahi L Garcia; Karen Lloyd; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; streamlined genome; aquatic bacteria; single cell genomics; metagenomics; evolutionary genomics; salinity; Baltic Sea; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : This thesis investigates the evolutionary processes of streamlined genomes from aquatic bacteria adapting to different salinities, using two groups of ultra-small aquatic bacteria (LD12 Alphaproteobacteria and acI Actinobacteria). Due to difficulties in obtaining pure cultures of these bacteria, culture-free approaches (single-cell genomics and metagenomics) were used to construct and compare genomes, and to study the mechanisms and selective forces of adaptation to freshwater, brackish, and marine ecosystems. LÄS MER

  4. 18. Antibiotic resistance in the environment: a contribution from metagenomic studies

    Författare :Johan Bengtsson-Palme; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistance; metagenomics; bioinformatics; next generation sequencing; resistance selection;

    Sammanfattning : Antibiotic resistance accounts for hundreds of thousands of deaths annually, and its projected increase has made the WHO recognize it as a major global health threat. In the last decade, evidence has mounted suggesting that the environment plays an important role in the progression of resistance. LÄS MER

  5. 19. Culture-independent methods and high-throughput sequencing applied to evolutionary microbial genomics

    Författare :Anders E. Lind; Thijs JG Ettema; Purificación López-García; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Single cell genomics; metagenomics; amplicon; archaea; haloarchaea; endosymbiosis; ciliate; hydrogenosome; tree reconciliation;

    Sammanfattning : Culture-independent methods allow us to better understand the diversity of microorganisms on earth. By omitting the culturing step, we can gain access to species previously out of our reach.To better capture and understand the diversity of microorganisms, we have developed an alternative to 16S amplicon sequencing. LÄS MER

  7. 20. Microbial Ecosystem Functions Along the Steep Oxygen Gradient of the Landsort Deep, Baltic Sea

    Författare :Petter Thureborn; Sara Sjöling; Mats Grahn; Matthias Labrenz; Södertörns högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; microbial ecology; ecosystem functions; microbial community; bacteria; archaea; metagenomics; metatranscriptomics; oxygen gradient; hypoxia; sediment; Baltic Sea; Environmental Studies; Miljövetenskapliga studier; Östersjö- och Östeuropaforskning; Baltic and East European studies;

    Sammanfattning : Through complex metabolic interactions aquatic microbial life is essential as a driver of ecosystem functions and hence a prerequisite for sustaining plant and animal life in the sea and on Earth. Despite its ecological importance, infor­mation on the complexity of microbial functions and how these are related to environmental conditions is limited. LÄS MER