Sökning: "Metagenome"

Visar resultat 6 - 10 av 20 avhandlingar innehållade ordet Metagenome.

  1. 6. Enabling massive genomic and transcriptomic analysis

    Författare :Henrik Stranneheim; Joakim Lundeberg; Elaine Mardis; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA; RNA; sequencing; massively parallel sequencing; alignment; assembly; single nucleotide polymorphism; LHON;

    Sammanfattning : In recent years there have been tremendous advances in our ability to rapidly and cost-effectively sequence DNA. This has revolutionized the fields of genetics and biology, leading to a deeper understanding of the molecular events in life processes. LÄS MER

  3. 7. Microbial Biofilms in the Bioinformatics Era

    Författare :Kemal Sanli; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; metagenomics; bioinformatics software; microbial biofilms; Next Generation Sequencing; pathway analysis; periphyton; marine biofilms; FANTOM; PACFM; PACFM;

    Sammanfattning : Adverse effects of anthropogenic impact on the environment have become conspicuous in the past century and among others include the gradual increase in the global CO2 levels, the contamination of air, soil and water by toxic chemicals, and the emergence of antimicrobial resistance among pathogenic microbial species. Microorganisms partake in an extreme diversity of activities in the environment, and hence, constitute the prime candidates to be investigated in understanding of the progression and effects of the aforementioned environmental hazard scenarios. LÄS MER

  4. 8. Analysis of large-scale metagenomic data

    Författare :Fredrik Boulund; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metagenomics; DNA analysis; big data; antibiotic resistance; hidden Markov models; high-performance computing; distributed computing; distributed computing;

    Sammanfattning : The topic of this thesis is the analysis of large data sets of DNA sequence data produced from modern high-throughput DNA sequencing machines. Using such machines to sequence the genetic content of a microbial community produces a metagenome. This thesis comprises three research papers, all connected to the study of large metagenomic data sets. LÄS MER

  5. 9. Bacterial Degradation and Use of Chitin in Aquatic Habitats

    Författare :Sara Beier; Stefan Bertilsson; Ian Head; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chitin; organic matter degradation; microbial ecology; functional guild; Biology; Biologi;

    Sammanfattning : Chitin belongs to the most abundant biopolymers on earth where it has an important role as a structural element in crustaceans, insects, fungi and some phytoplankton. Missing evidence for long-term accumulation of chitin in nature implies fast turnover and as chitin is composed of aminosugar subunits it holds central roles in both carbon and nitrogen cycles. LÄS MER

  7. 10. Machine learning and data-parallel processing for viral metagenomics

    Författare :Zurab Bzhalava; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : More than 2 million cancer cases around the world each year are caused by viruses. In addition, there are epidemiological indications that other cancer-associated viruses may also exist. However, the identification of highly divergent and yet unknown viruses in human biospecimens is one of the biggest challenges in bio- informatics. LÄS MER