Sökning: "Metabolic syndrome"

Visar resultat 6 - 10 av 273 avhandlingar innehållade orden Metabolic syndrome.

  1. 6. Genetics of type 2 diabetes and the metabolic syndrome

    Författare :Mia Klannemark; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; PDE3B; PPARG; LPL; metabolic syndrome; diabetes; genetic; HSL; UCP2; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Type 2 diabetes and the metabolic syndrome are highly prevalent disorders with severe complications such as cardiovascular disease. The aetiology of type 2 diabetes and the metabolic syndrome is not known, but the interaction between genetic factors and environmental triggers is important. LÄS MER

  3. 7. Aspects of Plasminiogen Activator Inhibitor 1 in Metabolic Syndrome

    Författare :Karin Mossberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PAI-1; metabolic syndrome; obesity; type 2 diabetes; cardiovascular disease; fibrinolysis; thrombi; plasma; platelets; adipose tissue; mRNA; qPCR; reference gene;

    Sammanfattning : Plasminogen activator inhibitor 1 (PAI-1) is the main inhibitor of the fibrinolytic system and binds irreversibly to tissue-type plasminogen activator (t-PA), and thereby inhibits the protective action of t-PA against thrombus formation. Elevated levels of plasma PAI-1 is observed in subjects with type 2 diabetes (T2D) and the metabolic syndrome (MetS), which is a combination of metabolic features including obesity. LÄS MER

  4. 8. Molecular mechanisms in obesity-associated metabolic disease

    Författare :Louise Olofsson; Göteborgs universitet; []
    Nyckelord :obesity; metabolic syndrome; cholesterol; resting metabolic rate; insulin resistance; serum amyloid A; S100 calcium binding protein A1; Zn-alpha2-glycoprotein; CCAAT enhancer binding protein alpha;

    Sammanfattning : Obesity is associated with increased morbidity and mortality. Subjects with obesity are at risk of developing several serious conditions such as type 2 diabetes, hypertension, coronary heart disease and stroke. LÄS MER

  5. 9. Clinical Manifestations of Coronary Heart Disease and the Metabolic Syndrome : A Population-based Study in Middle-aged Men in Uppsala

    Författare :Kristina Dunder; Lars Lind; Hans Lithell; Annika Rosengren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; coronary heart disease; metabolic syndrome; insulin resistance; antihypertensive treatment; risk score; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : During the past decades the knowledge concerning risk factors and pathophysiology of coronary heart disease (CHD) has substantially increased. However, despite identification of important risk factors CHD remains the leading cause of death in the western world. LÄS MER

  7. 10. Polycystic ovary syndrome : A study on factors of potential impact on body fat and carbohydrate metabolism

    Författare :Gianluca Gennarelli; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; polycystic ovary syndrome; androgens; insulin; insulin resistance; body fat distribution; hypoglycaemia; adrenal; cortisol; ACTH; leptin; gestational diabetes mellitus; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; Obstetrics and Gynaecology; obstetrik och gynekologi;

    Sammanfattning : The aim of the present thesis was to investigate some factors underlying the metabolic, anthropometric, and endocrine abnormalities of women with the polycystic ovary syndrome (PCOS).An iv insulin tolerance test (0.15 IU bolus) showed substantially preserved glucose counterregulation in women with PCOS (n=18). LÄS MER