Sökning: "Metabolic Profiling"

Visar resultat 6 - 10 av 66 avhandlingar innehållade orden Metabolic Profiling.

  1. 6. Functional Profiling Of Metabolic Regulation In Marine Bacteria

    Författare :Saraladevi Muthusamy; Jarone Pinhassi; Torsten Thomas; Sarala Devi Muthusamy; Institutionen för biologi och miljö (BOM) Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; marine microbiology; physiology; heterotrophic bacteria; adaptive strategies; survival; proteomics; growth phase; proteorhodopsin; inorganic sulphur oxidation; anaplerotic CO2 fixation; Miljövetenskap; Environmental Science;

    Sammanfattning : Oceans are powered by active, metabolically diverse microorganisms, which are important in regulating biogeochemical cycles on Earth. Most of the ocean surface is often limited by nutrients, influencing bacterial growth and activities. LÄS MER

  3. 7. Multivariate profiling of metabolites in human disease : Method evaluation and application to prostate cancer

    Författare :Elin Thysell; Henrik Antti; Janne Lehtiö; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolite profiling; metabolomics; predictive metabolomics; mass spectrometry; GC-MS; biomarkers; chemometrics; design of experiments; multivariate data analysis; prostate cancer; bone metastases; plasma; biologisk kemi; biological chemistry;

    Sammanfattning : There is an ever increasing need of new technologies for identification of molecular markers for early diagnosis of fatal diseases to allow efficient treatment. In addition, there is great value in finding patterns of metabolites, proteins or genes altered in relation to specific disease conditions to gain a deeper understanding of the underlying mechanisms of disease development. LÄS MER

  4. 8. Vitreoscilla Haemoglobin. Genetic Fusions and Metabolic Characterisation

    Författare :Viktoria Roos; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Metabolism; Biokemi; metabolism; osmotic stress; transcript profiling; DNA microarrays; random elongation mutagenesis; directed evolution; mRNA structure; Vitreoscilla haemoglobin VHb ; Escherichia coli; salt stress.;

    Sammanfattning : Vitreoscilla is an obligate aerobic bacterium living in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla expresses a homodimeric haemoglobin (VHb) when subjected to oxygen-limited conditions. LÄS MER

  5. 9. Industrial Systems Biology and Metabolic Engineering of Saccharomyces cerevisiae

    Författare :José Manuel Otero; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metabolic engineering; industrial systems biology; Saccharomyces cerevisiae;

    Sammanfattning : Saccharomyces cerevisiae is the most well characterized eukaryote, the preferred microbial cell factoryfor the largest industrial biotechnology product (bioethanol), and a robust commercially compatible scaffold to be exploited for diverse chemical production. Succinic acid is a highly sought after added-value chemical whichis not overproduced in native S. LÄS MER

  7. 10. β-N-methylamino-L-alanine (BMAA)-induced neurotoxicity : Studies in vitro and in vivo

    Författare :Lisa Ersson; Malin Andersson; Eva B Brittebo; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; BMAA; neurotoxin; neurodegeneration; cellular transport; metabolic profiling; protein-association; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : β-N-methylamino-L-alanine (BMAA) is a neurotoxic non-proteinogenic amino acid produced naturally by cyanobacteria, diatoms and dinoflagellates and it has been detected in samples from fresh and marine water from all over the world. It can bioaccumulate in fish and shellfish, and has a potential to biomagnify in a terrestrial food chain. LÄS MER