Sökning: "Membrane protein biogenesis"

Visar resultat 1 - 5 av 51 avhandlingar innehållade orden Membrane protein biogenesis.

  1. 1. Membrane Protein Biogenesis in Escherichia coli : A proteomics approach

    Författare :David Vikström; Jan-Willem de Gier; Eitan Bibi; Stockholms universitet; []
    Nyckelord :SRP; YidC; SecE; Membrane protein biogenesis; protein targeting; 2D BN SDS-PAGE; Biochemistry; biokemi;

    Sammanfattning : In the bacterium Escherichia coli all proteins are synthesized in the cytoplasm. However, at least 25% of them then need to be exported to another cellular compartment where they exert their function. E. coli has several different targeting pathways to ensure the correct localization of its proteins. LÄS MER

  3. 2. Membrane protein topogenesis

    Författare :Karin Öjemalm; Gunnar von Heijne; Tracy Palmer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Sammanfattning : The membranes of cells are highly complex and heterogeneous structures that fulfill multiple vital tasks. They form thin barriers that seal out the environment, thus defining the cell’s boundaries. LÄS MER

  4. 3. Cotranslational protein biogenesis in Escherichia coli monitored by force profile analysis

    Författare :Felix Nicolaus; Gunnar von Heijne; Ross Dalbey; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; cotranslational protein biogenesis; membrane protein; soluble protein; transmembrane helices; force profile analysis; arrest peptide; biokemi; Biochemistry;

    Sammanfattning : Proteins are a diverse class of biomolecules that carry out many essential functions across all organisms. They can either be found in aqueous compartments or embedded in biological membranes of the cell and are called soluble or membrane proteins, respectively. LÄS MER

  5. 4. Membrane-bound proteins : Characterization, evolution, and functional analysis

    Författare :Misty M. Attwood; Helgi B. Schiöth; Arne Elofsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transmembrane protein; alpha-helical membrane protein; evolution membrane proteins; 3TM; 4TM; 5TM; trispanin; Bioinformatics; Bioinformatik;

    Sammanfattning : Alpha-helical transmembrane proteins are important components of many essential cell processes including signal transduction, transport of molecules across membranes, protein and membrane trafficking, and structural and adhesion activities, amongst others. Their involvement in critical networks makes them the focus of interest in investigating disease pathways, as candidate drug targets, and in evolutionary analyses to identify homologous protein families and possible functional activities. LÄS MER

  7. 5. Protein production in the E. coli cell envelope

    Författare :Thomas Baumgarten; Jan-Willem de Gier; Dirk-Jan Scheffers; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; E. coli; protein biogenesis; recombinant proteins; membrane proteins; secretory proteins; protein displays; outer membrane vesicles; Biochemistry; biokemi;

    Sammanfattning : Proteins fulfil essential functions in every cell and malfunctioning proteins are often the cause of diseases. On the other hand, proteins like antibody fragments or hormones can be used to treat diseases. LÄS MER