Sökning: "Melphalan prodrug"
Hittade 2 avhandlingar innehållade orden Melphalan prodrug.
1. Preclinical Studies of the Melphalan Prodrug J1 for Cancer Therapy
Sammanfattning : J1 (L-melphalanyl-L-p-fluorophenylalanyl ethyl ester) is a dipeptide derivative of the alkylating agent melphalan with increased cytotoxicity. In this thesis the preclinical pharmacology of J1 has been characterized.Our results show that J1 rapidly enters the cells, where melphalan is released by hydrolysis. LÄS MER
2. Potential New Drugs in Lymphoma
Sammanfattning : Lymphomas are malignant tumours arising from cells in the lymphatic system. They are classified as B-cell lymphomas, T-cell lymphomas and Hodgkin lymphoma (HL). Of the B-cell lymphomas, one of the most common is diffuse large B-cell lymphoma (DLBCL). LÄS MER