Sökning: "Melatonin"
Visar resultat 6 - 10 av 55 avhandlingar innehållade ordet Melatonin.
6. The Duodenal Mucosal Bicarbonate Secretion : Role of Melatonin in Neurohumoral Control and Cellular Signaling
Sammanfattning : The duodenal lumen is exposed to aggressive factors with a high potential to cause damage to the mucosa. Bicarbonate secretion by the duodenal mucosa is accepted as the primary important defense mechanism against the hydrochloric acid intermittently expelled from the stomach. LÄS MER
7. Role of Inducible Nitric Oxide Synthase and Melatonin in Regulation of β-cell Sensitivity to Cytokines
Sammanfattning : The mechanisms of β-cell destruction leading to type 1 diabetes are complex and not yet fully understood, but infiltration of the islets of Langerhans by autoreactive immune cells is believed to be important. Activated macrophages and T-cells may then secrete cytokines and free radicals, which could selectively damage the β-cells. LÄS MER
8. Regulation of Duodenal Mucosal Barrier Function and Motility : The Impact of Melatonin
Sammanfattning : The duodenal mucosa is regularly exposed to acid, digestive enzymes and ingested noxious agents. It is thus critical to maintain a protective barrier to prevent the development of mucosal injury and inflammation, which are often observed in situations when barrier function is impaired. LÄS MER
9. Role of Melatonin, Neuropeptide S and Short Chain Fatty Acids in Regulation of Duodenal Mucosal Barrier Function and Motility
Sammanfattning : The duodenal epithelium is regularly exposed to HCl, digestive enzymes, bacteria and toxins, and sometimes also to ethanol and drugs. The imbalance of aggressive factors in the intestinal lumen and mucosal barrier function increases the risk of tissue injury and inflammation. LÄS MER
10. New pharmacological aspects of melatonin
Sammanfattning : Melatonin is a hormone that takes part in the regulation of biological rhythms. It is produced in the pineal gland and is stimulated by darkness and inhibited by exposure to light. LÄS MER