Sökning: "Megalencephaly"

Hittade 2 avhandlingar innehållade ordet Megalencephaly.

1. 1. The megencephaly mouse : from gene to neuronal proliferation

   Författare :Ann-Sophie Persson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Megalencephaly; epilepsy; mouse model; genetics; voltage gated potassium channel; hippocampus; proliferation;

   Sammanfattning : Megalencephaly, enlarged brain, can be associated with a wide range of symptoms from benign to severe. Severe cases are often associated with mental retardation and seizures. The megencephaly mouse shows a dramatic, progressive increase in size of the hippocampus and ventral cortex. LÄS MER

3. 2. Megencephaly, significance, biology and identification of a genetic cause

   Författare :Susanna Petersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Megalencephaly; brain; mceph; ion-channel; DNA; mutation; truncation; frameshift; seizure; plasticity; neurotrophin; growth factor; neuropeptide; positional cloning;

   Sammanfattning : Enlarged brain is termed megencephaly or megalencephaly, and is defined as a brain volume above the 98th percentile. It is a major sign in several neurological diseases with symptoms ranging from very mild to lethal, including mental retardation, low intelligence, motoric and neurological disturbances, seizures and dysmorphic features. LÄS MER