Sökning: "Megakaryopoiesis"

Hittade 3 avhandlingar innehållade ordet Megakaryopoiesis.

  1. 1. Programming Blood Cell Fates. Insights from Direct Lineage Conversion and Development

    Författare :Sandra Capellera Garcia; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic development; Erythropoiesis; Megakaryopoiesis; Direct Lineage Conversion;

    Sammanfattning : Red blood cells (RBC) and platelets constitute the non-immune branch of the hematopoietic system and are responsible for the vital functions of transporting oxygen to the tissues and clotting blood vessel injuries, respectively. These cells are produced during embryonic development and throughout life through a process called hematopoiesis which is tightly regulated by extrinsic and intrinsic factors. LÄS MER

  3. 2. Neonatal thrombocytopenia : from bleeding risk to new therapies on the horizon

    Författare :Emöke Deschmann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Thrombocytopenia is common in the Neonatal Intensive Care Unit and if severe, it is treated with platelet transfusions to prevent bleeding. Previous studies found a weak correlation between thrombocytopenia and incidence of bleeding. LÄS MER

  4. 3. Mesenchymal niche contribution to normal and malignant hematopoiesis

    Författare :Lakshmi Sandhow; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Normal hematopoiesis is tightly regulated by hematopoietic microenvironment/niche in bone marrow (BM) via direct hematopoietic cell-niche cell interaction and factors secreted by various types of cellular niches. The BM niche consists of cells of mesenchymal cell origin including mesenchymal stem cells (MSCs) and progenitor cells (MPCs). LÄS MER