Sökning: "Medicinska Fakulteten Lunds Universitet"

Visar resultat 1 - 5 av 32 avhandlingar innehållade orden Medicinska Fakulteten Lunds Universitet.

  1. 1. Interactions between Streptococcus pyogenes and the Human Immune System

    Författare :Maria Weineisen; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; virologi; mykologi; Immunology; mycology; Mikrobiologi; bakteriologi; virology; Biomedicinska vetenskaper; Neutrophils; Streptococcus pyogenes; Biomedical sciences; Phagocytosis; bacteriology; Microbiology; Integrins;

    Sammanfattning : Streptococcus pyogenes is a common human pathogen causing mild infections such as tonsillitis and pharyngitis, but is also the cause of life-threatening conditions. To be able to infect the human host, S. pyogenes express different virulence factors. The surface-expressed M protein is a major virulence factor of S. LÄS MER

  3. 2. Antigen presenting cells in autoimmune diabetes: phenotype, function and modulation by Linomide

    Författare :Eva Dahlén; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; secreting systems; Endocrinology; Linomide; costimulation; TNF-a; dendritic cells; Diabetes; macrophages; diabetology; Endokrinologi; sekretion; diabetologi; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : The aim of this thesis was to better understand the role of antigen presenting cells (APC) in the development of diabetes in the nonobese diabetic (NOD) mouse. We have shown that DC and Mphi that infiltrate the islets of Langerhans produce tumour necrosis factor-a (TNF-a), a cytokine known to contribute to the pathogenesis in the early stages of diabetes development. LÄS MER

  4. 3. Basement membrane components in the chondrocyte extracellular matrix

    Författare :Alexander Kvist; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skelett; rheumatology locomotion; nidogen; chondroitin sulfate; collagen assembly; Skeleton; muscle system; type IV collagen; laminin; perlecan; basement membranes; ECM; chondrcytes; muskelsystem; reumatologi;

    Sammanfattning : The extracellular matrix (ECM) is a network of macromolecules which, together with cells, forms the various tissues of all metazoan organisms. Cartilage, in contrast to most other tissues, contains relatively few cells in proportion to the volume occupied by ECM. LÄS MER

  5. 4. Staphylococcal enterotoxin H - structure and function of a superantigen

    Författare :Helen Pettersson; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; TCR; staphylococcal enterotoxin H; MHC class II; superantigen; transplantation; Immunologi; serologi; serology;

    Sammanfattning : The aim of this thesis was to characterise the biological functions of the superantigen staphylococcal enterotoxin H (SEH). Superantigens are highly immunostimulatory proteins, which crosslink T cells and antigen presenting cells (APCs). LÄS MER

  7. 5. Nitric oxide in central nervous structures associated with water balance and micturition

    Författare :Anders Nylén; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacological sciences; spinal projections; True Blue; cystometry; circumventricular organs; paraventricular nucleus; supraoptic nucleus; NADPH diaphorase; immunohistochemistry; oxytocin; 8-arginine-vasopressin; hypothalamus; rat; micturition; nitric oxide; water balance; neuronal nitric oxide synthase; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : The role of nitric oxide (NO) in the central control of water balance and micturition has not yet been established. In the present thesis, where female rats were used, neuronal NO synthase (nNOS) distribution was studied in structures of the central nervous system known to be associated with the above mentioned control. LÄS MER