Sökning: "Medicinsk laboratorievetenskap"
Visar resultat 6 - 10 av 123 avhandlingar innehållade orden Medicinsk laboratorievetenskap.
6. Structural properties of the mastoid using image analysis and visualization
Sammanfattning : The mastoid, located in the temporal bone, houses an air cell system whose cells have a variation in size that can go far below current conventional clinical CT scanner resolution. Therefore, the mastoid air cell system is only partially represented in a CT scan. LÄS MER
7. Characterizing the pancreatic "isletome" : 3D optical imaging to study diabetes
Sammanfattning : The pancreas is a specialised multipurpose organ, that can be separated into two major compartments: endocrine and exocrine. The exocrine part makes up the majority of the organ volume and functions to secrete digestive enzymes into the small intestine. LÄS MER
8. High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities
Sammanfattning : High-throughput drug screening (HTS) in live cells is often a vital part of the preclinical anticancer drug discovery process. So far, two-dimensional (2D) monolayer cell cultures have been the most prevalent model in HTS endeavors. However, 2D cell cultures often fail to recapitulate the complex microenvironments of in vivo tumors. LÄS MER
9. Evolution of protein and non-coding RNA genes studied with comparative genomics
Sammanfattning : The identification of protein and non-coding RNA (ncRNA) genes is one important step in the analysis of a genome. This thesis focuses on the identification and analysis of proteins and ncRNAs homologues by exploiting a variety of computational methods in order to reach conclusions as to their structure, function, evolution and regulation. LÄS MER
10. New ultrasonographic approaches to monitoring cardiac and vascular function
Sammanfattning : Atherosclerotic cardiovascular disease is the leading cause of death worldwide. To decrease mortality and morbidity in cardiovascular disease, the development of accurate, non-invasive methods for early diagnosis of atherosclerotic cardiac and vascular engagement is of considerable clinical interest. LÄS MER