Sökning: "Medicinsk bioteknologi Biomedicinsk laboratorievetenskap teknologi"

Visar resultat 1 - 5 av 117 avhandlingar innehållade orden Medicinsk bioteknologi Biomedicinsk laboratorievetenskap teknologi.

  1. 1. Decision Support for Treatment of Patients with Advanced Parkinson’s Disease

    Författare :Jerker Westin; Torgny Groth; Mark Dougherty; Sven Pålhagen; Marja-Liisa Dahl; Martin Rydmark; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; telemedicine; motor test; tapping; spiral; self-assessment; home-assessment; outcome measure; electronic diary; patient-reported outcome; remote patient monitoring; levodopa; infusion; pharmacokinetic; pharmacodynamic; Medical informatics; Medicinsk informatik; Medical Informatics; Medicinsk informatik; E-MOTIONS; Beslutsstöd för Parkinsonbehandling;

    Sammanfattning : The overall aim of this thesis was to develop, deploy and evaluate new IT-based methods for supporting treatment and assessment of treatment of advanced Parkinson’s disease. In this condition a number of different motor and non-motor symptoms occur in episodes of varying frequency, duration and severity. LÄS MER

  3. 2. Structural properties of the mastoid using image analysis and visualization

    Författare :Olivier Cros; Michael Gaihede; Hans Knutsson; Bernard Ars; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The mastoid, located in the temporal bone, houses an air cell system whose cells have a variation in size that can go far below current conventional clinical CT scanner resolution. Therefore, the mastoid air cell system is only partially represented in a CT scan. LÄS MER

  4. 3. Characterizing the pancreatic "isletome" : 3D optical imaging to study diabetes

    Författare :Max Hahn; Ulf Ahlgren; András Gorzsás; Leif Carlsson; Alvin C. Powers; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3D imaging; fluorescence microscopy; 3D image analysis; technique development; diabetes; Islet of Langerhans; Insulin; β-cell mass; pancreas; anatomy; molecular medicine medical sciences ; molekylär medicin medicinska vetenskaper ; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : The pancreas is a specialised multipurpose organ, that can be separated into two major compartments: endocrine and exocrine. The exocrine part makes up the majority of the organ volume and functions to secrete digestive enzymes into the small intestine. LÄS MER

  5. 4. High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities

    Författare :Wojciech Senkowski; Mårten Fryknäs; Rolf Larsson; Peter Nygren; Mats Gustafsson; Krister Wennerberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; spheroids; high-throughput screening; nitazoxanide; OXPHOS; gene expression profiling; statins; drug repositioning; 3D cell culture; quiescent cells; Medical Science; Medicinsk vetenskap;

    Sammanfattning : High-throughput drug screening (HTS) in live cells is often a vital part of the preclinical anticancer drug discovery process. So far, two-dimensional (2D) monolayer cell cultures have been the most prevalent model in HTS endeavors. However, 2D cell cultures often fail to recapitulate the complex microenvironments of in vivo tumors. LÄS MER

  7. 5. Superantigens in group A streptococcus : gene diversity and humoral immune response

    Författare :Linda Maripuu; Mari Norgren; Susan Hollingshead; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Group A streptococcus; Streptococcus pyogenes; superantigen SAg ; SAg-gene profile; M-protein; emm-genotype; biomedicinsk laboratorievetenskap; biomedical laboratory science;

    Sammanfattning : Group A streptococcus (GAS) is a strictly human pathogen that causes infections ranging from asymptomatic carriage to the highly lethal streptococcal toxic shock syndrome (STSS). GAS are classified according to the sequence of the variable 5’ end of the emm-gene that encodes the surface associated M-protein. LÄS MER