Sökning: "Medicin och hälsovetenskap Medicinsk bioteknologi Biomedicinsk laboratorievetenskap teknologi"

Visar resultat 21 - 25 av 117 avhandlingar innehållade orden Medicin och hälsovetenskap Medicinsk bioteknologi Biomedicinsk laboratorievetenskap teknologi.

  1. 21. Single Molecule Detection : Microfluidic Automation and Digital Quantification

    Författare :Malte Kühnemund; Mats Nilsson; Ulf Landegren; Sten Linnarsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single molecule; digital; rolling circle amplification; magnetic particle; padlock probe; microfluidics; resistive pulse sensing; lab on chip; mobile phone microscopy; enrichment; sequencing;

    Sammanfattning : Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, which now permit the detection and analysis of single molecules with high sensitivity and specificity. Assay sensitivity is fundamentally limited by the efficiency of the detection method used for read-out. LÄS MER

  2. 22. Superantigens in group A streptococcus : gene diversity and humoral immune response

    Författare :Linda Maripuu; Mari Norgren; Susan Hollingshead; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Group A streptococcus; Streptococcus pyogenes; superantigen SAg ; SAg-gene profile; M-protein; emm-genotype; biomedicinsk laboratorievetenskap; biomedical laboratory science;

    Sammanfattning : Group A streptococcus (GAS) is a strictly human pathogen that causes infections ranging from asymptomatic carriage to the highly lethal streptococcal toxic shock syndrome (STSS). GAS are classified according to the sequence of the variable 5’ end of the emm-gene that encodes the surface associated M-protein. LÄS MER

  3. 23. Application of Proximity Ligation Assay for Multidirectional Studies on Transforming Growth Factor-β Pathway

    Författare :Agata Zieba; Ola Söderberg; Kathleen C. Flanders; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proximity ligation; TGF-β signaling; Smad; single cell analysis; cell cycle; context-dependent signaling; CRC; Molekylär cellbiologi; Molecular Cellbiology; Medicinal Chemistry; Läkemedelskemi; Molecular Biology; Molekylärbiologi;

    Sammanfattning : A comprehensive understanding of how the body and all its components function is essential when this knowledge is exploited for medical purposes. The achievements in biological and medical research during last decades has provided us with the complete human genome and identified signaling pathways that governs the cellular processes that facilitates the development and maintenance of higher order organisms. LÄS MER

  4. 24. Modeling of Intraluminal Surfaces of Thoracic Aortas

    Författare :Johan Bondesson; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; aneurysm; TEVAR; bird-beaking; cardiac pulsatility; geometric modeling; surface curvature; endograft; stereolithographic surface; dissection; Thoracic aorta;

    Sammanfattning : Vascular diseases are getting more and more common as a result of modern-day lifestyle and the fact that the population is getting older. One of the newest treatments for vascular diseases such as aneurysms and dissections is endovascular repair with endografting. LÄS MER

  5. 25. Cold-Electron Bolometers fabricated with Direct Write Technology for Microwave Receiver systems

    Författare :Ernst Otto; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : This thesis concerns the development of microwave detector technology for cosmology instruments and THz imaging, including fabrication of SIN tunnel junctions for thermometry and bolometric detectors, and also phase switch circuits as a part of integrated microwave receiver systems. Cold-Electron Bolometers (CEB) based on Superconductor-Insulator-Normal metal (SIN) tunnel junctions have been developed for employment in sub-millimeter astronomical receivers. LÄS MER