Sökning: "Medical and Physiological Chemistry"

Visar resultat 21 - 25 av 36 avhandlingar innehållade orden Medical and Physiological Chemistry.

  1. 21. C4b-binding protein: Identification of binding sites and a possible function of the interaction with protein S

    Författare :Joanna Webb; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical chemistry; apoptosis; binding sites; complement; C4b-binding protein; protein S; Klinisk kemi;

    Sammanfattning : The subject of this thesis is plasma protein C4b-binding protein (C4BP). C4BP is an important regulator of the classical pathway of the complement system, a cascade-like system comprised of over 35 proteins, which partakes in the defence against micro-organisms and is involved of clearance of immune-complexes and apoptotic cells. LÄS MER

  2. 22. Applications of multi-component condensations and development of polyamine synthesis on solid-phase

    Författare :Daniel Jönsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Solid-phase synthesis of small non-polymeric molecules has become increasingly important as a tool in the development of pharmacologically active compounds. Of particular interest are the syntheses of compounds with low molecular weight, low polarity and a reduced flexibility of the functional groups, i.e. LÄS MER

  3. 23. Apolipoprotein M – Studies of Structure and Function

    Författare :Josefin Ahnström; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal peptidase; signal peptide; crystallization; Apolipoprotein; lipocalin; HDL; coronary heart disease;

    Sammanfattning : Apolipoprotein M (apoM), a 25 kDa plasma protein, is found in all major lipoprotein classes, although the majority is found in high density lipoproteins (HDL). ApoM has been suggested to be involved in the formation of and adding to the antiatherogenic functions of HDL, but its function is still not completely known. LÄS MER

  4. 24. Inductively Coupled Plasma Atomic Emission Spectrometry : Exploring the Limits of Different Sample Preparation Strategies

    Författare :Barbro Kollander; Jean Pettersson; Marit Andersson; Jonas Bergquist; Grethe Wibetoe; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; multi element analysis; trace element; ICP-AES; inductively coupled plasma atomic emission spectromtery; water analysis; liver analysis; non digested samples; medical samples; biological samples; samples from biopsies and autopsies; mice organ; fast analysis; internal standard; preconcentration; matrix elimination; Cu; Zn; Mn; Co; Pb; Cd; Mg; Ca; Fe; Ni; Cr; S; P; K; Al; Analytical chemistry; Analytisk kemi; Analytical Chemistry; Analytisk kemi;

    Sammanfattning : This thesis describes two different sample preparation strategies for inductively coupled plasma atomic emission spectrometry (ICP-AES), and their ability regarding multi element quantification in complex samples. Sensitivity, repeatability, reproducibility and accuracy were investigated. LÄS MER

  5. 25. Vanadate and Peroxovanadate Complexes of Biomedical Relevance : A speciation approach with focus on diabetes

    Författare :András Gorzsás; Lage Pettersson; Carlos F. G. C. Geraldes; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Inorganic chemistry; vanadium; hydrogen peroxide; lactate; citrate; phosphate; alanyl serine; picolinic acid; speciation; formation constants; equilibrium; solution structure; potentiometry; NMR 51V; 31P; 13C; 1H ; Oorganisk kemi; Inorganic chemistry; Oorganisk kemi; oorganisk kemi; Inorganic Chemistry;

    Sammanfattning : Diabetes mellitus is one of the most threatening epidemics of modern times with rapidly increasing incidence. Vanadium and peroxovanadium compounds have been shown to exert insulin–like actions and, in contrast to insulin, are orally applicable. However, problems with side–effects and toxicity remain. LÄS MER